CLEC5A

  • Official Full Name

    C-type lectin domain family 5, member A

  • Overview

    This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008]
  • Synonyms

    CLEC5A; C-type lectin domain family 5, member A; MDL1; MDL-1; CLECSF5; C-type lectin domain family 5 member A; C-type lectin superfamily member 5; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • NS0
  • Wheat Germ
  • Fc
  • GST
  • His
  • Avi
  • mFc
  • N
  • 9×His
  • hFc
  • Non
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLEC5A-12H Active Recombinant Human CLEC5A Protein, Tyr26-Lys188, N-9×His tagged NS0 N-9×His Tyr26-Lys188
Human CLEC5A-6345H Recombinant Human CLEC5A protein, hFc-tagged HEK293 N-hFc Tyr26-Lys188
Human CLEC5A-11321H Recombinant Human CLEC5A, His-tagged E.coli His 32-188a.a.
Human CLEC5A-1472H Recombinant Human CLEC5A Protein, GST-tagged Wheat Germ GST
Human CLEC5A-20H Recombinant Human CLEC5A Protein, 28-188aa, C-His tagged Insect Cell His 28-188aa
Human CLEC5A-2162HF Recombinant Full Length Human CLEC5A Protein, GST-tagged In Vitro Cell Free System GST 188 amino acids
Human CLEC5A-1926H Recombinant Human CLEC5A protein, His-tagged HEK293 His Pro 28 - Lys 188
Mouse Clec5a-06M Active Recombinant Mouse Clec5a protein, His-tagged Mammalian cells His Tyr26-Lys190
Mouse CLEC5A-3571M Recombinant Mouse CLEC5A Protein Mammalian Cell His
Mouse Clec5a-1749M-B Recombinant Mouse Clec5a Protein Pre-coupled Magnetic Beads HEK293
Mouse Clec5a-1749M Recombinant Mouse Clec5a Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Mouse Clec5a-8564M Recombinant Mouse Clec5a protein, hFc-tagged HEK293 N-hFc Tyr26-Lys190
Mouse CLEC5A-1750M Recombinant Mouse CLEC5A Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Mouse CLEC5A-1750M-B Recombinant Mouse CLEC5A Protein Pre-coupled Magnetic Beads HEK293
Rat Clec5a-21R Recombinant Rat Clec5a, His tagged Human Cell Fc Val30-Lys190
Rat CLEC5A-860RCL Recombinant Rat CLEC5A cell lysate Human Cell Non
Rat CLEC5A-1344R Recombinant Rat CLEC5A protein(Val30-Lys190), His-tagged HEK293 His Val30-Lys190
Cynomolgus Monkey CLEC5A-86C Recombinant Cynomolgus CLEC5A, Fc tagged Human Cell Non Pro28-Arg188
Cynomolgus Monkey CLEC5A-87C Recombinant Cynomolgus CLEC5A, His tagged Human Cell Fc Pro28-Arg188
Cynomolgus Monkey CLEC5A-815CCL Recombinant Cynomolgus CLEC5A cell lysate Human Cell Non
Rhesus CLEC5A-114R Recombinant Rhesus CLEC5A protein, His-tagged HEK293 His Pro28-Arg188
Rhesus CLEC5A-113R Recombinant Rhesus CLEC5A protein, mFc-tagged HEK293 mFc Pro28-Arg188
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CLEC5A involved in several pathways and played different roles in them. We selected most pathways CLEC5A participated on our site, such as DAP12 interactions, Immune System, Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DAP12 interactionsAGO2;DUSP4;SPNA1;CD300E;SIRPB1;DUSP7;FRS2A;PTPRA;GRAP2B
Immune SystemSIGIRR;LAIR2;RACGAP1;BTR06;KIF18A;TRAF7;CASP4;CTSH;IFI30
Innate Immune SystemS100A12;LY86;CLEC5A;LGALS3;S100B;NOD1;RNF216;NLRC5;NLRP4B

CLEC5A has several biochemical functions, for example, carbohydrate binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC5A itself. We selected most functions CLEC5A had, and list some proteins which have the same functions with CLEC5A. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingCLEC3B;MAG;Fcer2a;MAN2C1;LGALS2A;KLRC1;Cd209g;KLRA8;GRIFIN
virus receptor activityGPR172B;DAG1;CD4;SELPLG;MRC1;CR2;TNFRSF4;ACE2;ITGB6

CLEC5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC5A here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC5A.

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