COX5A involved in several pathways and played different roles in them. We selected most pathways COX5A participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Oxidative phosphorylation |
COX5AA; PPA1A; ATP6V0D1; ATP5IA; COX10; ATP6V0A1; NDUFV2; COX15; NDUFA4L2; NDUFB7 |
| Metabolic pathways |
CYP4A14; INPP1; PPCDC; AKR1C3; PMM1; MAT1A; NADSYN1; SAT1A.2; KL; UGT1A2 |
| Cardiac muscle contraction |
CACNA2D2; CACNA1D; TPM4; COX4I1; ATP1B1A; ATP1B1; UQCRC2B; SLC8A1; ATP1A1A.1; TNNC1B |
| Non-alcoholic fatty liver disease (NAFLD) |
IL1B; PRKAG1; NR1H3; INS2; NDUFB2; PIK3R3; COX7B2; NDUFB10; SDHB; IL1A |
| Alzheimers disease |
mt-Atp8; NDUFA7; COX8A; COX7B2; NDUFB2; NDUFB5; NDUFV1; COX8C; NDUFS4; ADAM10 |
| Parkinsons disease |
VDAC2; COX7A1; SDHA; COX6B2; SLC18A1; CASP9; SDHB; UBA1; NDUFA3; SLC25A31 |
| Huntingtons disease |
NDUFS6; SLC25A5; HDAC1; NRF1; ATP5G3; DNALI1; UQCRH; UQCR10; POLR2I; NDUFB5 |
COX5A has several biochemical functions, for example, cytochrome-c oxidase activity, electron carrier activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COX5A itself. We selected most functions COX5A had, and list some proteins which have the same functions with COX5A. You can find most of the proteins on our site.
| Function |
Related Protein |
| cytochrome-c oxidase activity |
COX5AA; SURF1; COX8A; COX5B; COX7A2A; COA6; COX6B2; COX5B2; COX7A3; COX6A1 |
| electron carrier activity |
PHGDH; NDUFS6; NDUFS3; COX7A2A; NDUFV2; ACADL; AOX3L1; PTGES2; POR; AOX3 |
| metal ion binding |
EYA4; MMP25; CACNA1H; CYP4T8; AMDHD2; PRDM6; CNBPA; KCNIP3B; PVALB1; MBTD1 |
| protein binding |
RAB3B; CBX1; TMEM11; KLC3; TCERG1; LILRB2; CRY2; ZNHIT6; POP5; SLC7A1 |
COX5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX5A here. Most of them are supplied by our site. Hope this information will be useful for your research of COX5A.
KRT31; KRT40; EXOSC8; 40038273; MT-CO2; VHL; PINX1; TMBIM4; PDE4DIP; COPS6; Cenpe; SYNCRIP; env
Ren, JC; Rebrin, I; et al. Cytochrome c oxidase loses catalytic activity and structural integrity during the aging process in Drosophila melanogaster. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 401:64-68(2010).
Helling, S; Vogt, S; et al. Phosphorylation and kinetics of mammalian cytochrome c oxidase. MOLECULAR & CELLULAR PROTEOMICS 7:1714-1724(2008).
