Cyclooxygenase Activity Luminometric Assay Kit Kit-0254

September 27-30, 2022

Boston Convention and Exhibition Center

Booth #336

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Cyclooxygenase Activity Luminometric Assay Kit


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Cat.No. : Kit-0254 Optional Service: Optional requirements on this protein
Product Overview : The Cyclooxygenase (COX) Activity Assay Kit (Luminometric) is a non-radioactive COX activity assay. This kit allows user to easily evaluate COX I and COX II inhibitors in a convenient 96-well plate based assay with COX Activity Assay Kit (Luminometric) uses a specific chemiluminescent substrate to detect the peroxidative activity of COX enzymes. After inhibition by NSAIDs, the direct residual activity of COX is measured by addition of a proprietary luminescent substrate and arachidonic acid. Light emission starts immediately and is directly proportional to the COX activity in the sample. The chemiluminescent signal is measured over 5 seconds.
Size : 1 x 96 tests
Description : COX (cyclooxygenase, also known as Prostaglandin G/H synthase) is a membrane-bound enzyme responsible for the oxidation of arachidonic acid to Prostaglandin G2 (PGG2) and the subsequent reduction of PGG2 to PGH2. These reactions are the first steps in the formation of a variety of prostanoids.COX has been shown to be expressed in at least two different isoforms: a constitutively expressed form, COX1, and an inducible form, COX2. COX1 is thought to regulate a number of "housekeeping" functions such as vascular hemostasis and renal blood flow. Inflammation mediators such as growth factors, cytokines and endotoxin induce COX2 expression in a number of cellular systems.
Applications : Functional Studies more details
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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