Recombinant Human COX5A cell lysate

• Cat.No.: COX5A-389HCL

Specification

• Description: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: COX5A cytochrome c oxidase subunit Va [ Homo sapiens ]
• Official Symbol: COX5A
• Synonyms: COX5A; cytochrome c oxidase subunit Va; cytochrome c oxidase subunit 5A, mitochondrial; cytochrome c oxidase polypeptide Va; mitochondrial cytochrome c oxidase subunit Va; cytochrome c oxidase polypeptide, mitochondrial; VA; COX; COX-VA
• Gene ID: 9377
• mRNA Refseq: NM_004255
• Protein Refseq: NP_004246
• MIM: 603773
• UniProt ID: P20674
• Chromosome Location: 15q25
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Arachidonate Epoxygenase / Epoxide Hydrolase, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Cytochrome c oxidase, organism-specific biosystem; Cytochrome c oxidase, conserved biosystem
• Function: cytochrome-c oxidase activity; electron carrier activity; metal ion binding