CRABP1
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Official Full Name
cellular retinoic acid binding protein 1
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Overview
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. -
Synonyms
CRABP1; cellular retinoic acid binding protein 1; cellular retinoic acid binding protein 1 , RBP5; cellular retinoic acid-binding protein 1; CRABP; CRABP I; CRABPI; cellular retinoic acid-binding protein I; RBP5; CRABP-I;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Mouse
- Wheat Germ
- Fc
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CRABP1 Related Articles
CRABP1 involved in several pathways and played different roles in them. We selected most pathways CRABP1 participated on our site, such as RA biosynthesis pathway, Signal Transduction, Signaling by Retinoic Acid, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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RA biosynthesis pathway | RDH7;ADH8B;DHRS9;ALDH8A1;CYP26A1;RDH14;DHRS3A;CRABP1A;AKR1C21 |
Signal Transduction | DCLRE1B;FSTL3;EDNRAB;RPE65A;EMR1;INSL5;FMNL1;RHOF;AXL |
Signaling by Retinoic Acid | PDK3B;CRABP2A;RDH14B;DHRS4;RARG;FABP11A;CRABP1A;RDH13;RDH7 |
Vitamin A and carotenoid metabolism | BCO2;RDH12;CRABP2;DHRS3;CRABP1;RARG;RDH10;RBP7 |
CRABP1 has several biochemical functions, for example, protein binding, retinal binding, retinoic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRABP1 itself. We selected most functions CRABP1 had, and list some proteins which have the same functions with CRABP1. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | ARMC1;HLA-DRB3;ARHGAP5;DBC1;NRCAM;ROS1;SLAMF6;RPRD1A;HDDC2 |
retinal binding | RBP3;RBP2A;RBP2B;RBP4;RBP2;RBP5;CRABP2;RBP7;CRABP1 |
retinoic acid binding | CRABP1A;UGT1A9;PTGDSB;RARA;UGT1A3;UGT1A7;CYP26A1;CRABP2;UGT1A1 |
retinoid binding | RBP2;RBP4L;RBP1;LCN5;CRABP2;CRABP1;RBP5;RBP3;PTGDS |
retinol binding | RBP7;RBP4;RBP5;CRABP2;C8G;RBP2;ADH4;RBP1;ADH7 |
transporter activity | SLC5A6B;SLC22A23;IGF2R;FLVCR1;GABRA5;CLVS2;AP2S1;MUP20;ATP5G1 |
CRABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRABP1.
p27958-pro_0000037576; MPP3; TRA2A
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