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CRABP1

  • Official Full Name

    cellular retinoic acid binding protein 1

  • Overview

    This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
  • Synonyms

    CRABP1; cellular retinoic acid binding protein 1; cellular retinoic acid binding protein 1 , RBP5; cellular retinoic acid-binding protein 1; CRABP; CRABP I; CRABPI; cellular retinoic acid-binding protein I; RBP5; CRABP-I;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mouse
  • Wheat Germ
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CRABP1-26984TH Recombinant Human CRABP1 E.coli N/A
Human CRABP1-1828H Recombinant Human CRABP1 Protein, GST-tagged Wheat Germ GST
Human CRABP1-11550H Recombinant Human CRABP1, His-tagged E.coli His 1-137a.a.
Human CRABP1-481H Recombinant Human cellular retinoic acid binding protein 1 E.coli N/A
Human CRABP1-202H Recombinant Human CRABP1, None tagged E.coli Fc
Human CRABP1-197HCL Recombinant Human CRABP1 lysate HEK293 N/A
Human CRABP1-2248HF Recombinant Full Length Human CRABP1 Protein, GST-tagged In Vitro Cell Free System GST 137 amino acids
Human CRABP1-1800H Recombinant Human CRABP1 Protein (Met1-Glu137), N-His tagged E.coli N-His Met1-Glu137
Human CAB158 Mouse Anti-Human CRABP1 Monoclonal Antibody Mouse N/A
Human CRABP1-3675H Recombinant Human CRABP1 protein, GST-tagged E.coli GST 1-137 aa
Human CRABP1-2730H Recombinant Human CRABP1 protein, GST-tagged E.coli GST 2-137aa
Mouse CRABP1-3875M Recombinant Mouse CRABP1 Protein Mammalian Cell His
Mouse CRABP1-1954M-B Recombinant Mouse CRABP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse CRABP1-1954M Recombinant Mouse CRABP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CRABP1-1583R Recombinant Rat CRABP1 Protein Mammalian Cell His
Rat CRABP1-1240R Recombinant Rat CRABP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CRABP1-1240R-B Recombinant Rat CRABP1 Protein Pre-coupled Magnetic Beads HEK293
Chicken CRABP1-2253C Recombinant Chicken CRABP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CRABP1 Related Articles

CRABP1 involved in several pathways and played different roles in them. We selected most pathways CRABP1 participated on our site, such as RA biosynthesis pathway, Signal Transduction, Signaling by Retinoic Acid, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RA biosynthesis pathwayRDH7;ADH8B;DHRS9;ALDH8A1;CYP26A1;RDH14;DHRS3A;CRABP1A;AKR1C21
Signal TransductionDCLRE1B;FSTL3;EDNRAB;RPE65A;EMR1;INSL5;FMNL1;RHOF;AXL
Signaling by Retinoic AcidPDK3B;CRABP2A;RDH14B;DHRS4;RARG;FABP11A;CRABP1A;RDH13;RDH7
Vitamin A and carotenoid metabolismBCO2;RDH12;CRABP2;DHRS3;CRABP1;RARG;RDH10;RBP7

CRABP1 has several biochemical functions, for example, protein binding, retinal binding, retinoic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRABP1 itself. We selected most functions CRABP1 had, and list some proteins which have the same functions with CRABP1. You can find most of the proteins on our site.

Function Related Protein
protein bindingARMC1;HLA-DRB3;ARHGAP5;DBC1;NRCAM;ROS1;SLAMF6;RPRD1A;HDDC2
retinal bindingRBP3;RBP2A;RBP2B;RBP4;RBP2;RBP5;CRABP2;RBP7;CRABP1
retinoic acid bindingCRABP1A;UGT1A9;PTGDSB;RARA;UGT1A3;UGT1A7;CYP26A1;CRABP2;UGT1A1
retinoid bindingRBP2;RBP4L;RBP1;LCN5;CRABP2;CRABP1;RBP5;RBP3;PTGDS
retinol bindingRBP7;RBP4;RBP5;CRABP2;C8G;RBP2;ADH4;RBP1;ADH7
transporter activitySLC5A6B;SLC22A23;IGF2R;FLVCR1;GABRA5;CLVS2;AP2S1;MUP20;ATP5G1

CRABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRABP1.

p27958-pro_0000037576; MPP3; TRA2A

Hattori, T; Uchida, C; et al. Distinct and Site-Specific Phosphorylation of the Retinoblastoma Protein at Serine 612 in Differentiated Cells. PLOS ONE 9:-(2014).
Leitch, VD; Dwivedi, PP; et al. Retinol-binding protein 4 downregulation during osteogenesis and its localization to non-endocytic vesicles in human cranial suture mesenchymal cells suggest a novel tissue function. HISTOCHEMISTRY AND CELL BIOLOGY 139:75-87(2013).
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