ddost Protein, dolichyl-diphosphooligosaccharide--protein glycosyltransferase

ddost

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ddost

Official Full Name dolichyl-diphosphooligosaccharide--protein glycosyltransferase
Background This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Synonyms DDOST; dolichyl-diphosphooligosaccharide--protein glycosyltransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; KIAA0115; MGC2191; OK/SW-cl.45; OST; OST48; WBP1; AGE R1; DDOST 48 kDa subunit; Dolichyl-diphosphooligosaccharide-protein glycosyltransferase; EC 2.4.1.119; Oligosaccharyl transferase 48 kDa subunit; RP23-25C1.4; wu:fa11d01; zgc:66068; zgc:77478; advanced glycation endproduct receptor 1; oligosaccharyltransferase 48 kDa subunit; dolichyl-diphosphooligosaccharide-protein glycotransferase; AGER1; OKSWcl45
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DDOST-1127H Recombinant Human DDOST, None tagged E.coli N/A
    Human DDOST-11884H Recombinant Human DDOST, His-tagged E.coli His
    Human DDOST-211H Recombinant Human DDOST Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DDOST-2451H Recombinant Human DDOST Protein, GST-tagged Wheat Germ GST
    Human DDOST-7024HCL Recombinant Human DDOST 293 Cell Lysate HEK293 N/A
    Mouse Ddost-1653M Recombinant Mouse Ddost protein, His-tagged E.coli His
    Mouse DDOST-4392M Recombinant Mouse DDOST Protein Mammalian Cell His
    Rat DDOST-1814R Recombinant Rat DDOST Protein Mammalian Cell His
    Chicken DDOST-4040C Recombinant Chicken DDOST Mammalian Cell His
    Zebrafish DDOST-12319Z Recombinant Zebrafish DDOST Mammalian Cell His

    ddost involved in several pathways and played different roles in them. We selected most pathways ddost participated on our site, such as AGE/RAGE pathway, Advanced glycosylation endproduct receptor signaling, Asparagine N-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ddost were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    AGE/RAGE pathway DIAPH1; ATF2; CHUK; JUN; AGER; DDOST; LGALS3; JAK2; MAPK14; TIRAP
    Advanced glycosylation endproduct receptor signaling S100A12; AGER; DDOST; SAA1; APPB; ALCAMB; LGALS3; S100B; APPA
    Asparagine N-linked glycosylation SEC23IP; GORASP1; TRAPPC2; MIA3; NAPB; CNIH3; TRAPPC4; SEC22C; DPAGT1; OS9
    Gene Expression ZCRB1; CLNS1A; HUG; SURF1; NR5A1B; ZNF563; ZNF3; ADARB1; DNMT3L; ZNF596
    Immune System DEFB119; CTSO; ARIH2; ASB14; TRIM45; TRIM9; ASB3; KIF2A; EIF4G2; CRCP
    Innate Immune System CLEC6A; BTR02; CLEC5A; DEFB106A; FAM49BA; ABI1; FCN3; TAX1BP1B; BTR16; SUGT1
    Metabolic pathways NDUFAB1; GCNT2; CPS1; DNMT3A; MGAT1; CYP26A1; FLAD1; NDUFB3; RIMKLA; CYP2C37
    Metabolism of proteins PFDN2; GALNT5; ADD1; ST6GALNAC1.2; ADAMTS15; TBCA; MPDU1B; EEF1G; BCHE; SPON1

    ddost has several biochemical functions, for example, contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity, contributes_to oligosaccharyl transferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ddost itself. We selected most functions ddost had, and list some proteins which have the same functions with ddost. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity STT3A; RPN2; RPN1; TUSC3; OSTC; DAD1; DDOST
    contributes_to oligosaccharyl transferase activity DAD1; DDOST
    protein binding PNMA2; PCBD2; TRIM16; TOR1AIP1; ZNF576; SPTSSB; RUSC1-AS1; OTUB2; RTN4R; KDM4A

    ddost has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ddost here. Most of them are supplied by our site. Hope this information will be useful for your research of ddost.

    TMEM173; SEC27; copa_schpo; 7242199; PGRMC1; SAP18; RFXANK; PTP4A3; TNFRSF1A; TNFRSF1B; MCC; HLA-B; MAGEA6; BRCC3; COP1; EIF6; ARF6; SMYD3; TMBIM4

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