Recombinant Human DDOST Protein, GST-tagged

• Cat.No.: DDOST-2451H
• Product Overview: Human DDOST full-length ORF ( NP_005207.2, 1 a.a. - 456 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.1 kDa
• AA Sequence: MGYFRCAGAGSFGRRRKMEPSTAAR AWALFWLLLPLLGAVCASGPRTLVL LDNLNVRETHSLFFRSLKDRGFELT FKTADDPSLSLIKYGEFLYDNLIIF SPSVEDFGGNINVETISAFIDGGGS VLVAASSDIGDPLRELGSECGIEFD EEKTAVIDHHNYDISDLGQHTLIVA DTENLLKAPTIVGKSSLNPILFRGV GMVADPDNPLVLDILTGSSTSYSFF PDKPITQYPHAVGKNTLLIAGLQAR NNARVIFSGSLDFFSDSFFNSAVQK AAPGSQRYSQTGNYELAVALSRWVF KEEGVLRVGPVSHHRVGETAPPNAY TVTDLVEYSIVIQQLSNGKWVPFDG DDIQLEFVRIDPFVRTFLKKKGGKY SVQFKLPDVYGVFQFKVDYNRLGYT HLYSSTQVSVRPLQHTQYERFIPSA YPYYASAFSMMLGLFIFSIVFLHMK EKEKSD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase [ Homo sapiens ]
• Official Symbol: DDOST
• Synonyms: DDOST; dolichyl-diphosphooligosaccharide--protein glycosyltransferase; dolichyl diphosphooligosaccharide protein glycosyltransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; KIAA0115; OST; OST48; WBP1; DDOST 48 kDa subunit; advanced glycation endproduct receptor 1; oligosaccharyltransferase 48 kDa subunit; oligosaccharyl transferase 48 kDa subunit; dolichyl-diphosphooligosaccharide-protein glycotransferase; dolichyl-diphosphooligosaccharide-protein glycosyltransferase; AGER1; CDG1R; OKSWcl45; MGC2191
• Gene ID: 1650
• mRNA Refseq: NM_005216
• Protein Refseq: NP_005207
• MIM: 602202
• UniProt ID: P39656