DPP6

  • Official Full Name

    dipeptidyl-peptidase 6

  • Overview

    This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  • Synonyms

    DPP6; dipeptidyl-peptidase 6; VF2; DPPX; dipeptidyl aminopeptidase-like protein 6; DPP VI; dipeptidylpeptidase 6; dipeptidyl peptidase VI; dipeptidyl peptidase IV-related protein; dipeptidyl aminopeptidase IV-related protein;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DPP6-12147H Recombinant Human DPP6, His-tagged E.coli His 120-353a.a.
Human DPP6-1055H Recombinant Human DPP6 protein, His & T7-tagged E.coli His/T7 Phe667~Asp865 (Accession # P42658)
Human DPP6-2847H Recombinant Human DPP6 Protein, GST-tagged Wheat Germ GST
Human DPP6-3851H Recombinant Human DPP6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DPP6-2537H Recombinant Human DPP6 Protein Variant 1 HEK293 N/A
Human DPP6-2536H Recombinant Human DPP6 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DPP6-304H Recombinant Human DPP6 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human DPP6-784H Recombinant Human DPP6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DPP6-784H-B Recombinant Human DPP6 Protein Pre-coupled Magnetic Beads HEK293
Human DPP6-1125HFL Recombinant Full Length Human DPP6 Protein, C-Flag-tagged Mammalian cells Flag
Human DPP6-3592H Recombinant Human DPP6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DPP6-1983H Recombinant Human DPP6 Protein (Phe667-Asp865), N-His tagged E.coli N-His Phe667-Asp865
Human DPP6-4126HF Recombinant Full Length Human DPP6 Protein, GST-tagged In Vitro Cell Free System GST 180 amino acids
Mouse Dpp6-2642M Recombinant Mouse Dpp6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DPP6-1944R Recombinant Rat DPP6 Protein Mammalian Cell His
Rat DPP6-1603R Recombinant Rat DPP6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DPP6-1603R-B Recombinant Rat DPP6 Protein Pre-coupled Magnetic Beads HEK293
Rat DPP6-1946R Recombinant Rat DPP6 protein, His-tagged Yeast His 111-859 aa
Rat DPP6-1945R Recombinant Rat DPP6 protein, His-tagged E.coli His 111-859 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

DPP6 involved in several pathways and played different roles in them. We selected most pathways DPP6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DPP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DPP6 has several biochemical functions, for example, NOT dipeptidyl-peptidase activity, potassium channel regulator activity, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DPP6 itself. We selected most functions DPP6 had, and list some proteins which have the same functions with DPP6. You can find most of the proteins on our site.

Function Related Protein
NOT dipeptidyl-peptidase activityDPP6;DPP10
potassium channel regulator activityKCNMB3;KCNV1;ARPP19;PRKCZ;KCNMB4;KCNIP4;KCNE2;SGK1;CHP
serine-type peptidase activityKLK7;PARLA;HPN;KLK1B22;PRSS12;TMPRSS11G;DPP6;SEC11C;GZMK

DPP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPP6.

PHB

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