Recombinant Full Length Human DPP6 Protein, C-Flag-tagged

• Cat.No.: DPP6-1125HFL
• Product Overview: Recombinant Full Length Human DPP6 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 97.4 kDa
• AA Sequence: MASLYQRFTGKINTSRSFPAPPEAS HLLGGQGPEEDGGAGAKPLGPRAQA AAPRERGGGGGGAGGRPRFQ YQARSDGDEEDELVGSNPPQRNWKG IAIALLVILVICSLIVTSVILLTPA EDNSLSQKKKVTVEDLFSED FKIHDPEAKWISDTEFIYREQKGTV RLWNVETNTSTVLIEGKKIESLRAI RYEISPDREYALFSYNVEPI YQHSYTGYYVLSKIPHGDPQSLDPP EVSNAKLQYAGWGPKGQQLIFIFEN NIYYCAHVGKQAIRVVSTGK EGVIYNGLSDWLYEEEILKTHIAHW WSPDGTRLAYAAINDSRVPIMELPT YTGSIYPTVKPYHYPKAGSE NPSISLHVIGLNGPTHDLEMMPPDD PRMREYYITMVKWATSTKVAVTWLN RAQNVSILTLCDATTGVCTK KHEDESEAWLHRQNEEPVFSKDGRK FFFIRAIPQGGRGKFYHITVSSSQP NSSNDNIQSITSGDWDVTKI LAYDEKGNKIYFLSTEDLPRRRQLY SANTVGNFNRQCLSCDLVENCTYFS ASFSHSMDFFLLKCEGPGVP MVTVHNTTDKKKMFDLETNEHVKKA INDRQMPKVEYRDIEIDDYNLPMQI LKPATFTDTTHYPLLLVVDG TPGSQSVAEKFEVSWETVMVSSHGA VVVKCDGRGSGFQGTKLLHEVRRRL GLLEEKDQMEAVRTMLKEQY IDRTRVAVFGKDYGGYLSTYILPAK GENQGQTFTCGSALSPITDFKLYAS AFSERYLGLHGLDNRAYEMT KVAHRVSALEEQQFLIIHPTADEKI HFQHTAELITQLIRGKANYSLQIYP DESHYFTSSSLKQHLYRSII
  NFFVECFRIQDKLPTVTAKEDEEED TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease, Transmembrane

Gene Information

• Gene Name: DPP6 dipeptidyl peptidase like 6 [ Homo sapiens (human) ]
• Official Symbol: DPP6
• Synonyms: VF2; DPL1; DPPX; MRD33
• Gene ID: 1804
• mRNA Refseq: NM_130797.4
• Protein Refseq: NP_570629.2
• MIM: 126141
• UniProt ID: P42658