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Official Full Name dopamine receptor D5
Background This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. This receptor is neuron specific, localized primarily within limbic regions of the brain. Defects in DRD5 are a cause of blepharospasm and may be a cause of schizophrenia.
Synonyms DRD5; dopamine receptor D5; DBDR; DRD1B; DRD1L2; MGC10601; D(1B) dopamine receptor; OTTHUMP00000158603; dopamine D5 receptor; dopamine receptor D1B; d(5) dopamine receptor; D1beta dopamine receptor
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DRD5-12165H Recombinant Human DRD5, His-tagged E.coli His
    Human DRD5-12H Recombinant Human DRD5 Wheat Germ N/A
    Human DRD5-13H Recombinant Human DRD5, GST-tagged E.coli GST
    Human DRD5-6816HCL Recombinant Human DRD5 293 Cell Lysate HEK293 N/A
    Rat DRD5-1959R Recombinant Rat DRD5 Protein Mammalian Cell His
    Kit-0962 TR-FRET LXR alpha Coactivator Assay Kit, rabbit N/A
    Kit-1071 Deubiquitinase Activity Assay Kit (Fluorometric) N/A
    Kit-1218 DRD5 CHO-K1 β-Arrestin GPCR Assay Kit N/A
    Kit-1219 cAMP DRD5 CHO-K1 GPCR Assay Kit N/A

    drd5 involved in several pathways and played different roles in them. We selected most pathways drd5 participated on our site, such as Amine ligand-binding receptors, Calcium signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with drd5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amine ligand-binding receptors CHRM5; DRD4; CHRM1; HRH3; DRD3; TAAR1; ADRB1; CHRM2; ADRB3; ADRA2C
    Calcium signaling pathway PTGER1A; NOS2B; NOS2A; PRKCA; GNA15.4; ADRB2B; SLC8A2B; HTR4; VDAC3; PPP3R2
    Class A/1 (Rhodopsin-like receptors) PENK; AMCF-II; HEBP1; ADORA2B; FFAR3; DRD5; OPN1SW1; OPN1LW; EDNRA; NMBB
    Dopamine receptors DRD2; DRD5; DRD3; DRD1; DRD4
    Dopaminergic synapse PPP2R5D; PLCB1; CAMK2A; CREB3L1; PRKCB; CAMK2G; PPP3CA; ITPR3; KCNJ5; PPP2R5A
    G alpha (s) signalling events PTH; CRHB; RAMP2; RAMP1; CRHR1; VIP2; SCT; RAMP3; CALCRL; ADORA2B
    GPCR downstream signaling RGS19; QRFP; PRKCHB; AMCF-II; ADM2; HCRT; CCR1; GPR18; OR4D2; PENK
    GPCR ligand binding RGR; OPN4A; EMR1; CYSLTR1; CRHR1; NMS; ADCYAP1R1; EDN2; FZD10; SCT

    drd5 has several biochemical functions, for example, G-protein coupled amine receptor activity, dopamine binding, dopamine neurotransmitter receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by drd5 itself. We selected most functions drd5 had, and list some proteins which have the same functions with drd5. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled amine receptor activity GPR21; DRD4-RS; DRD5; TAAR7F; DRD1A; TAAR6; TAAR9; TAAR8B; DRD1; DRD4
    dopamine binding GPR143; DRD4; TH; DRD1; DRD2A; DRD2; DRD5; DRD1B; SLC6A3; ADRB2
    dopamine neurotransmitter receptor activity DRD4; DRD2L; DRD2B; DRD2A; DRD4A; DRD7; DRD5; DRD4B; DRD1A; DRD1B
    dopamine neurotransmitter receptor activity, coupled via Gs DRD1; DRD1B; DRD5; DRD1A

    drd5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with drd5 here. Most of them are supplied by our site. Hope this information will be useful for your research of drd5.

    Hawi, Z; RCummins, TD; et al. The molecular genetic architecture of attention deficit hyperactivity disorder. MOLECULAR PSYCHIATRY 20:289-297(2015).
    Sriram, K; Jefferson, AM; et al. Neurotoxicity following acute inhalation of aerosols generated during resistance spot weld-bonding of carbon steel. INHALATION TOXICOLOGY 26:720-732(2014).

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