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Official Full Name ephrin-A4
Background This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified.
Synonyms EFNA4; ephrin-A4; EPLG4; LERK4; LERK-4; ligand of eph-related kinase 4; eph-related receptor tyrosine kinase ligand 4; EFL4; FLJ57652; MGC125826
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Human Cell
    • Mammalian cells
    • Tag :
    • Fc
    • GST
    • His
    • T7
    • human
    • IgG1
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EFNA4-001HCL Recombinant Human EFNA4 cell lysate Human Cell N/A
    Human EFNA4-1380H Recombinant Human EFNA4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human EFNA4-151H Recombinant Human Ephrin-A4 E.coli N/A
    Human EFNA4-1610H Recombinant Human Ephrin-A4 Mammalian cells N/A
    Human EFNA4-177H Recombinant Human EFNA4 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human EFNA4-323H Recombinant Human EFNA4 protein, His-tagged HEK293 His
    Human EFNA4-3461H Recombinant Human EFNA4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human EFNA4-4336H Recombinant Human Ephrin-A4, GST-Tagged Human GST
    Mouse Efna4-050M Recombinant Mouse Efna4 Protein, Fc-tagged HEK293 Fc
    Mouse Efna4-051M Recombinant Mouse Efna4 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Efna4-1130M Recombinant Mouse Efna4 protein, His & GST-tagged E.coli His/GST
    Mouse EFNA4-2158MCL Recombinant Mouse EFNA4 cell lysate Human Cell N/A
    Mouse Efna4-4056M Recombinant Mouse Efna4, Fc tagged Human Cell Fc
    Mouse Efna4-4057M Recombinant Mouse Efna4, His tagged Human Cell His
    Mouse Efna4-440M Recombinant Mouse Ephrin A4 Mammalian cells N/A
    Rat Efna4-1131R Recombinant Rat Efna4 protein, His & T7-tagged E.coli His/T7
    Rat Efna4-1132R Recombinant Rat Efna4 protein, His & GST-tagged E.coli His/GST

    efna4 involved in several pathways and played different roles in them. We selected most pathways efna4 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with efna4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology LGI1; CSNK2A2; CDK5R1B; DLG3; MED10; MYL9; PEA15; LGI2; ARHGEF28; RANBP9
    EPH-Ephrin signaling EFNA5; CLTB; AP2B1; ARPC1A; EFNB3B; MYL12A; EFNA2A; CFL1; AP2A2; EFNB1
    EPH-ephrin mediated repulsion of cells EFNA3; EFNB2A; EFNA2A; AP2B1; AP2S1; EPHA2A; EFNB3; EFNB2; EFNA1B; EPHB3A
    EPHA-mediated growth cone collapse SHB; EFNA2; EFNA1; EFNA4; EFNA3; MYL12B; EPHA10; EFNA5; EPHA2; EFNA1B
    PI3K-Akt signaling pathway PIK3AP1; CHAD; COMP; CSF3; CSF1R; CSH1; PRP2; CSF1; CSF3R; CDC37
    Rap1 signaling pathway LOC608458; PFN4; EFNA4; CSF1; EFNA2; RGS14
    Ras signaling pathway RASA3; HTR7; PLA2G1B; PRKCA; PIK3CB; MET; PLA2G2E; PIK3R1; FGF17; PDGFRA

    efna4 has several biochemical functions, for example, ephrin receptor binding, protein binding, transmembrane-ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by efna4 itself. We selected most functions efna4 had, and list some proteins which have the same functions with efna4. You can find most of the proteins on our site.

    Function Related Protein
    ephrin receptor binding Anks1; EFNA4; EFNA3B; EFNA5; CDK5R1; FYN; PTPN1; EPHA4; NTRK3; EFNA1A
    protein binding GAS1; TRIM32; NCOA2; LTF; PSMA3; EPS15; RAB7; ETF1; WIPF1; TAF7
    transmembrane-ephrin receptor activity EPHB2; EPHB1; EFNA4; EPHA1; EPHA10; EFNA3; EPHA5; EFNB3; EPHA4

    efna4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with efna4 here. Most of them are supplied by our site. Hope this information will be useful for your research of efna4.


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