Active Recombinant Mouse Ephrin A4

• Cat.No.: Efna4-440M
• Product Overview: Recombinant Mouse Efna4protein was expressed in Murine myeloma cell line. Leu26-Gly176.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Non
• Protein Length: 26-176 a.a.
• Description: EphrinA4 isa member of the ephrin ligand family which binds members of the Eph receptorfamily. All ligands share a conserved extracellular sequence, which mostlikely corresponds to the receptor binding domain. This conserved sequenceconsists of approximately 125 amino acids and includes four invariantcysteines. The Aclass ligands have a GPI anchor following the conservedsequence. EphrinA4 has been shown to bind EphA2, EphA3, EphA4, EphA5, EphA6,EphA7, and EphB1.
• Form: Lyophilized from a0.2 um filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
• N-terminalSequence: Leu26
• MolecularWeight: 43.6 kDa
• Activity: Measuredby its binding ability in a functional ELISA. Immobilized rmEphA7/Fc Chimeraat 2 μg/mL (100 μL/well) can bind biotinylated rmEphrinA4/Fc Chimera with alinear range of 0.16 10 ng/mL.
• Endotoxin Level: <1.0EU per 1 μg of the protein by the LAL method.
• Purity: >95%,by SDSPAGE under reducing conditions and visualized by silver stain.
• Reconstitution: Reconstitute withsterile PBS at 200ug/mL.
• Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, 20 to 70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, 20 to70°C under sterile conditions after reconstitution.

Gene Information

• Gene Name: Efna4 ephrin A4 [ Musmusculus ]
• Official Symbol: Efna4
• Synonyms: Efna4; ephrin A4; Epl4;EFL-4; LERK-4; ephrin-A4; EPH-related receptor tyrosine kinase ligand 4
• Gene ID: 13639
• mRNA Refseq: NM_007910
• Protein Refseq: NP_031936
• UniProt ID: O08542
• Chromosome Location: 3 F1; 3 48.0 cM
• Pathway: Axon guidance
• Function: ephrin receptorbinding