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Official Full Name EPH receptor B2
Background Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Synonyms EPHB2; EPH receptor B2; DRT, EphB2 , EPHT3, ERK; ephrin type-B receptor 2; Hek5; Tyro5; EPH-like kinase 5; eph tyrosine kinase 3; elk-related tyrosine kinase; protein-tyrosine kinase HEK5; tyrosine-protein kinase TYRO5; renal carcinoma antigen NY-REN-47
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NSO
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • DDK
    • His
    • Fc
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EPHB2-001HCL Recombinant Human EPHB2 cell lysate Insect Cell N/A
    Human EPHB2-1106HCL Recombinant Human EPHB2 cell lysate Human Cell N/A
    Human EPHB2-12493H Recombinant Human EPHB2, GST-tagged E.coli GST
    Human EPHB2-26441TH Recombinant Human EPHB2, His-tagged His
    Human EPHB2-28579TH Recombinant Human EPHB2 N/A
    Human EPHB2-304H Recombinant Human EPH Receptor B2, GST-tagged, Active Sf9 Insect Cell GST
    Human EPHB2-3400H Recombinant Human EPHB2 Protein, GST-tagged Wheat Germ GST
    Human EPHB2-375H Recombinant Human EPHB2 Protein, DDK/His-tagged HEK293 DDK/His
    Human EPHB2-469H Recombinant Human EPHB2, ENLYFQ tagged Human Cell His
    Human EPHB2-542H Recombinant Human EPH Receptor B2, His-tagged Sf9 Insect Cell His
    Human EPHB2-693H Recombinant Human EPHB2, Fc-His tagged Human Cell Fc/His
    Human EPHB2-694H Recombinant Human EPHB2, His tagged Human Cell His
    Human EPHB2-7299H Recombinant Human EPHB2, His & GST tagged Insect Cell His/GST
    Mouse EPHB2-001MCL Recombinant Mouse EPHB2 cell lysate Human Cell N/A
    Mouse Ephb2-1727M Recombinant Mouse Eph Receptor B2 NSO N/A
    Mouse Ephb2-496M Recombinant Mouse Ephb2, Fc-tagged Human Cell Fc
    Mouse Ephb2-497M Recombinant Mouse Ephb2, His-tagged Human Cell His
    Chicken EPHB2-7095C Recombinant Chicken EPHB2 Mammalian Cell His
    Kit-1556 U2OS EphB2 Bioassay Kit N/A
    Kit-1583 EphB2 Functional Assay Kit N/A

    ephb2 involved in several pathways and played different roles in them. We selected most pathways ephb2 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with ephb2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance RANBP9; CFL2; NRG2A; GFRA1; EPHB4A; FGF20A; GFRA2; NFATC2; DUSP1; NETO2

    ephb2 has several biochemical functions, for example, ATP binding, protein binding, protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ephb2 itself. We selected most functions ephb2 had, and list some proteins which have the same functions with ephb2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ARHGAP33; RGP1; TPD52L2; CCDC94; UACA; PPP1R12C; ANK2; NKX3-1; SNTA1; OFCC1
    protein tyrosine kinase activity PTK7A; FGFR1OP; NEK1; CLK2; TYRO3; JAK2A; SRMS; FYNA; DYRK2; PTK6B
    transmembrane-ephrin receptor activity EPHA5; EPHA4; EPHA1; EFNA4; EFNB3; EPHB2; EPHA10; EFNA3; EPHB1

    ephb2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ephb2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ephb2.

    NUP153; ephopt; 24308301; RBL1; PTP4A2; MLLT4; pi3p; linkable pd173955 analogue; bosutinib; imatinib; purvalanol b; MAPK14

    Zhu, LF; Dissanayaka, WL; et al. Stimulation of EphB2/ephrin-B1 signalling by tumour necrosis factor alpha in human dental pulp stem cells. CELL PROLIFERATION 48:231-238(2015).
    Eriksson, O; Ramstrom, M; et al. The Eph Tyrosine Kinase Receptors EphB2 and EphA2 Are Novel Proteolytic Substrates of Tissue Factor/Coagulation Factor VIIa. JOURNAL OF BIOLOGICAL CHEMISTRY 289:-(2014).

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