ERCC3

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ERCC3

Official Full Name excision repair cross-complementation group 3
Background ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription. [provided by RefSeq, Jul 2008]
Synonyms ERCC3; excision repair cross-complementation group 3; XPB; BTF2; GTF2H; RAD25; TFIIH; TFIIH basal transcription factor complex helicase XPB subunit; BTF2 p89; TFIIH p89; TFIIH 89 kDa subunit; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; basic transcription factor 2 89 kDa subunit; xeroderma pigmentosum, complementation group B; xeroderma pigmentosum group B-complementing protein; TFIIH basal transcription factor complex 89 kDa subunit; excision repair cross-complementing rodent repair deficiency, complementation group 3;
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ERCC3-1692H Recombinant Human ERCC3 protein, His & T7-tagged E.coli His/T7
    Human ERCC3-2671H Recombinant Human ERCC3, His-tagged E.coli His
    Human ERCC3-30702TH Recombinant Human ERCC3 Wheat Germ N/A
    Human ERCC3-3459H Recombinant Human ERCC3 Protein, GST-tagged Wheat Germ GST
    Human ERCC3-6565HCL Recombinant Human ERCC3 293 Cell Lysate HEK293 N/A
    Mouse ERCC3-5286M Recombinant Mouse ERCC3 Protein Mammalian Cell His
    Rat ERCC3-2137R Recombinant Rat ERCC3 Protein Mammalian Cell His
    Cynomolgus Monkey ERCC3-494C Recombinant Cynomolgus ERCC3 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque ERCC3-1491R Recombinant Rhesus monkey ERCC3 Protein, His-tagged Mammalian Cell His
    Chicken ERCC3-1661C Recombinant Chicken ERCC3 Mammalian Cell His
    Zebrafish ERCC3-11564Z Recombinant Zebrafish ERCC3 Mammalian Cell His

    ERCC3 involved in several pathways and played different roles in them. We selected most pathways ERCC3 participated on our site, such as Basal transcription factors, Nucleotide excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERCC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Basal transcription factors GTF2H3-2; TAF1L; TAF8; GTF2H1; TAF10; TAF7L; GTF2H2C; MNAT1; GTF2H2; ERCC2
    Nucleotide excision repair RFC3; KIAA1530; CCNH; MCRS1; USP45; XPC; COPS7B; COPS8; RFC1; ERCC6

    ERCC3 has several biochemical functions, for example, 3-5 DNA helicase activity, ATP binding, ATP-dependent DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ERCC3 itself. We selected most functions ERCC3 had, and list some proteins which have the same functions with ERCC3. You can find most of the proteins on our site.

    Function Related Protein
    3-5 DNA helicase activity FBXO18; ERCC3; WRN; GINS1; CDC45
    ATP binding KIF12; PIK3CB; CKMT2A; NAGK; C9orf96; PRKCE; GRK1; SPG7; UCK2B; TSSK2
    ATP-dependent DNA helicase activity DDX3X; ERCC3; GTF2H4; BLM; FBXO18; CHD2; RECQL; BRIP1; XRCC6; RUVBL2
    ATPase activity ABCD1; EIF4A2; VCP; Abca2; SWSAP1; ATAD1A; ABCG2B; ERCC3; ATF7IP; HSPA1B
    DNA binding KDM2AA; PIAS1; PBX1; BHLHE22; TIGD6; HOMEZB; ZBTB1; NUSAP1; ZNF23; MSL3
    contributes_to DNA-dependent ATPase activity GTF2H3; ERCC3; GTF2H2; GTF2H4; RBBP4; BPTF; ERCC2; GTF2H1; MNAT1
    GTP binding RAB11A; GNAS; LRRK2; NMUR2; RAB13; RAB33BA; RAB12; TUBA8L2; RASD2; MXB
    contributes_to RNA polymerase II carboxy-terminal domain kinase activity ERCC3; GTF2H4; MNAT1; ERCC2; GTF2H2; GTF2H1; GTF2H3
    dATP binding ERCC3; HSP90AB1; ST13
    damaged DNA binding TP63; OGG1; TP53BP1; GTF2H3; RPS3; XRCC5; RAD1; CRY2; TRPC2; XRCC6
    peptide binding CRHBP; HCRTR1; AVPR2L; PPIB; CSNK1D; ERCC3; RPS6KB2; OXTRL; NPFFR2.1; ERAP2
    protein C-terminus binding ITGB3BP; PEX16; ATF4; NEIL1; DLG4; CITED1; MRE11A; TBL1X; ATXN2; MIF4GD
    protein N-terminus binding STX5A; PDCD10; PEX5; ERCC5; RELA; NFE2; ALOX5AP; TRAF6; PEX14; YWHAQ
    protein binding MC2R; PLRG1; TMEM199; PSMA4; PLIN1; TMEM132D; RAPGEF3; TBX24; GLRB; SNAI2
    contributes_to protein kinase activity GTF2H3; GTF2H1; ERCC2; GTF2H2; ERCC3; GTF2H4
    transcription factor binding HEY2; FOXA2; MECP2; HMGB1; NBN; GATA4; HMGA1; ZEB1; NEUROD1; PSMC5

    ERCC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERCC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERCC3.

    PSMC5; Psmc5; XIAP; CEP70; SRPK2; XPC; a8k1f4_human

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