Recombinant Full Length Human ERCC3 Protein

• Cat.No.: ERCC3-158HF
• Product Overview: Recombinant full length Human XPB with a N terminal proprietary tag; predicted MW: 112.09 kDa inclusive of tag. P19447,

Specification

• Description: ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 112.090kDa inclusive of tags
• Protein Length: 782 amino acids
• AA Sequence: MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPS AAGKQVDESGTKVDEYGAKDYRLQMPLKDDHTSRPLWVAP DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTA YSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCT VSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLR NSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQG KSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEEL QKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKR CLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKP IGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDL NFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYR EYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNP KINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRL GRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL VDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAAT DLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYME YHSSRSKAPSKHVHPLFKRFRK
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) [ Homo sapiens ]
• Official Symbol: ERCC3
• Synonyms: ERCC3; excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing); TFIIH basal transcription factor complex helicase XPB subunit; BTF2; GTF2H; RAD25; TFIIH; XPB
• Gene ID: 2071
• mRNA Refseq: NM_000122
• Protein Refseq: NP_000113
• MIM: 133510
• UniProt ID: P19447