Recombinant Mouse F11 Protein, His-tagged

• Cat.No.: F11-900M
• Product Overview: Recombinant Mouse F11 Protein(Pro157~Arg389) was expressed in E.coli with N-terminal His Tag.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His
• Form: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Molecular Mass: 30kDa
• Protein length: Pro157~Arg389
• Purity: >90% as determined by SDS-PAGE.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: F11 coagulation factor XI [ Mus musculus ]
• Official Symbol: F11
• Synonyms: F11; coagulation factor XI; PTA; plasma thromboplastin antecedent; FXI; Cf11; AI503996; 1600027G01Rik
• Gene ID: 109821
• mRNA Refseq: NM_028066
• Protein Refseq: NP_082342

Reviews

11/12/2021

The structure of the recombinant protein was analyzed by nuclear magnetic resonance (NMR), X-ray crystallography or electron microscopy, and the results showed that the protein was stable.

05/24/2021

In the process of purification, the removal of impurities is good.

05/17/2021

There are no structural or functional defects.

Q&As

Does F11 play a role in diabetes?

F11 plays an important role in diabetes, and abnormal levels may lead to insulin resistance and lipid metabolism disorders, which can lead to diabetes.

What are the mutation types of F11?

The mutation types of F11 include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

How to study the regulatory mechanism of F11?

Studying the regulatory mechanism of F11 requires the comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, protein interaction, etc.

What disease might abnormal F11 levels suggest?

Abnormal F11 levels may indicate some diseases related to lipid metabolism, such as diabetes, obesity, hyperlipidemia, etc.

How can the disease be treated by regulating F11 levels?

There are no drugs that directly regulate F11 levels, but they can be affected by lifestyle adjustments such as diet and exercise.

What is the relationship between F11 and other genes or proteins?

F11 has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.