Recombinant Human F12 protein, His-tagged
Cat.No. : | F12-12617H |
Product Overview : | Recombinant Human F12 protein(316-615 aa), fused with His tag, was expressed in E.coli. |
Availability | February 16, 2025 |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein length : | 316-615 aa |
AA Sequence : | MPAQPAPPKPQPTTRTPPQSQTPGA LPAKREQPPSLTRNGPLSCGQRLRK SLSSMTRVVGGLVALRGAHPYIAAL YWGHSFCAGSLIAPCWVLTAAHCLQ DRPAPEDLTVVLGQERRNHSCEPCQ TLAVRSYRLHEAFSPVSYQHDLALL RLQEDADGSCALLSPYVQPVCLPSG AARPSETTLCQVAGWGHQFEGAEEY ASFLQEAQVPFLSLERCSAPDVHGS SILPGMLCAGFLEGGTDACQGDSGG PLVCEDQAAERRLTLQGIISWGSGC GDRNKPGVYTDVAYYLAWIREHTVS |
Purity : | 85%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | F12 coagulation factor XII (Hageman factor) [ Homo sapiens ] |
Official Symbol : | F12 |
Synonyms : | F12; coagulation factor XII (Hageman factor); coagulation factor XII; Hageman factor; beta-factor XIIa part 1; beta-factor XIIa part 2; coagulation factor XIIa heavy chain; coagulation factor XIIa light chain; HAF; HAE3; HAEX; |
Gene ID : | 2161 |
mRNA Refseq : | NM_000505 |
Protein Refseq : | NP_000496 |
MIM : | 610619 |
UniProt ID : | P00748 |
Products Types
◆ Recombinant Protein | ||
F12-909M | Recombinant Mouse F12 Protein, His-tagged | +Inquiry |
F12-3606H | Recombinant Human F12 Protein, GST-tagged | +Inquiry |
F12-1833R | Recombinant Rat F12 Protein, His (Fc)-Avi-tagged | +Inquiry |
F12-2040P | Recombinant Pig F12 Protein (20-371 aa), His-tagged | +Inquiry |
F12-2005P | Recombinant Pig F12 Protein (20-371 aa), His-tagged | +Inquiry |
◆ Native Protein | ||
F12-13H | Native Human Factor beta-XIIa, Biotin Labeled | +Inquiry |
F12-5397H | Active Native Human Coagulation Factor XII (Hageman factor) | +Inquiry |
F12-28805TH | Native Human F12 | +Inquiry |
◆ Lysates | ||
F12-2115HCL | Recombinant Human F12 cell lysate | +Inquiry |
Related Gene
Not For Human Consumption!
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Customer Reviews (3)
Write a reviewTrustworthy data source. Valuable for our experiments.
Accelerates research progress. Exceptional service provider.
Enables data-driven decisions. A research necessity.
Q&As (7)
Ask a questionAbnormalities in F12 can lead to increased risk of thrombosis and related disorders.
Genetic mutations in F12 can result in either excessive bleeding or an increased tendency to form clots.
F12 works in conjunction with other coagulation factors and proteins to regulate clot formation and breakdown.
Altered F12 activity is associated with inflammation and can influence immune responses.
Targeting F12 offers potential in treating clotting disorders and reducing inflammation in certain conditions.
Upon activation, F12 triggers a series of enzymatic reactions leading to clot formation.
Factor XII (F12) activates the intrinsic pathway of the coagulation cascade, crucial for blood clot formation.
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