Native Human Factor beta-XIIa, Biotin Labeled
Cat.No. : | F12-13H |
Product Overview : | Human Factor beta-XIIa is activated from homogeneous Human Factor XII by an autoactivation process with Dextran Sulfate followed by repurification and biotinylation on lysine residues. |
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Source : | Human plasma |
Species : | Human |
Form : | Frozen liquid |
Molecular Mass : | 30,000 |
Purity : | >95% by SDS-PAGE analysis |
Usage : | For in vitro laboratory use only |
Notes : | Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. |
Storage : | -70°C |
Concentration : | 1.0 mg/ml |
Storage Buffer : | 4 mM Sodium Acetate; 0.15 M NaCl; pH 5.3 |
Shipping : | Dry ice |
Tag : | Non |
Gene Name : | F12 coagulation factor XII (Hageman factor) [ Homo sapiens ] |
Official Symbol : | F12 |
Synonyms : | F12; coagulation factor XII (Hageman factor); coagulation factor XII; Hageman factor; beta-factor XIIa part 1; beta-factor XIIa part 2; coagulation factor XIIa heavy chain; coagulation factor XIIa light chain; HAF; HAE3; HAEX; |
Gene ID : | 2161 |
mRNA Refseq : | NM_000505 |
Protein Refseq : | NP_000496 |
MIM : | 610619 |
UniProt ID : | P00748 |
Chromosome Location : | 5q33-qter |
Pathway : | Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem; Intrinsic Pathway, organism-specific biosystem; |
Function : | binding; misfolded protein binding; peptidase activity; protein binding; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
F12-2005P | Recombinant Pig F12 Protein (20-371 aa), His-tagged | +Inquiry |
F12-909M | Recombinant Mouse F12 Protein, His-tagged | +Inquiry |
F12-764H | Recombinant Human F12 protein, His-tagged | +Inquiry |
F12-2916M | Recombinant Mouse F12 Protein, His (Fc)-Avi-tagged | +Inquiry |
F12-2040P | Recombinant Pig F12 Protein (20-371 aa), His-tagged | +Inquiry |
◆ Native Protein | ||
F12-5397H | Active Native Human Coagulation Factor XII (Hageman factor) | +Inquiry |
F12-28805TH | Native Human F12 | +Inquiry |
◆ Lysates | ||
F12-2115HCL | Recombinant Human F12 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewTrustworthy data source. Valuable for our experiments.
Accelerates research progress. Exceptional service provider.
Enables data-driven decisions. A research necessity.
Q&As (7)
Ask a questionAbnormalities in F12 can lead to increased risk of thrombosis and related disorders.
Genetic mutations in F12 can result in either excessive bleeding or an increased tendency to form clots.
F12 works in conjunction with other coagulation factors and proteins to regulate clot formation and breakdown.
Altered F12 activity is associated with inflammation and can influence immune responses.
Targeting F12 offers potential in treating clotting disorders and reducing inflammation in certain conditions.
Upon activation, F12 triggers a series of enzymatic reactions leading to clot formation.
Factor XII (F12) activates the intrinsic pathway of the coagulation cascade, crucial for blood clot formation.
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