FABP1
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Official Full Name
fatty acid binding protein 1, liver
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Background
This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011] -
Synonyms
FABP1; fatty acid binding protein 1, liver; FABPL; L-FABP; fatty acid-binding protein, liver; fatty acid-binding protein 1; liver-type fatty acid-binding protein;
- Involved Pathway
- Protein Function
- Interacting Protein
- FABP1 Related Research Area
FABP1 involved in several pathways and played different roles in them. We selected most pathways FABP1 participated on our site, such as PPAR signaling pathway, Fat digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with FABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPAR signaling pathway | APOA2;FABP7B;ACAA1;FABP1;FABP1A;SCD5;Scd2;PDPK1B;ME1 |
| Fat digestion and absorption | PLA2G5;ABCA1;PLA2G12A;LIPF;PPAP2B;MTTP;PPAP2C;PLA2G1B;PLA2G3 |
FABP1 has several biochemical functions, for example, antioxidant activity, bile acid binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FABP1 itself. We selected most functions FABP1 had, and list some proteins which have the same functions with FABP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| antioxidant activity | APOM;CAT;S100A9;PRDX5;SEPW1;APOE;MT3;TRP53INP1;TP53INP1 |
| bile acid binding | FABP10A;PYGL;NR1H4;STARD5;PLA2G1B;AKR1C2;FABP6;FABP1;AKR1C21 |
| chromatin binding | SKI;GPR30;SP3;PBX2;SALL1;SMC1A;NFKB1;SUZ12;CBFA2T3 |
| drug binding | SRP54B;RARB;CHRNB2;FOLR1;MT2A;FNTB;GPR30;TLR8;P2RX2 |
| fatty acid binding | FABP5;LBFABP;FABP7B;ADH5;FABP4;FABP1B.1;GPR120;Alb;O3far1 |
| long-chain fatty acid transporter activity | FABP1;ABCD3;FABP3;ABCD3A;ABCD3B |
| phospholipid binding | PACSIN1A;ESYT1;ABCG1;PICALMA;F10;NR5A2;HIP1RB;SGIP1;FABP1 |
| protein binding | RNF175;POU3F2;TRP53;TAB2;SIAH1;HIST2H3C2;FBXL14;NCLN;WDR77 |
FABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FABP1.
FLNA; GRB2
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