• Official Full Name

    fibroblast growth factor 14

  • Background

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.
  • Synonyms

    FGF14; fibroblast growth factor 14; FHF4; SCA27; MGC119129; MGC129319; bA397O8.2; FHF 4; Fibroblast growth factor homologous factor 4; mFHF-4(1B); MGC129318; RP11-397O8.6; FHF-4; FGF-14;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Canine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Canine fgf14-169C Active Recombinant Canine fgf14 E.coli N/A
    Chicken FGF14-6341C Recombinant Chicken FGF14 Mammalian Cell His
    Human FGF14-4104H Recombinant Human FGF14 Protein, GST-tagged Wheat Germ GST
    Human FGF14-028H Recombinant Human FGF14 Protein E. coli
    Human FGF14-6246HCL Recombinant Human FGF14 293 Cell Lysate HEK293 N/A
    Human FGF14-6247HCL Recombinant Human FGF14 293 Cell Lysate HEK293 N/A
    Human FGF14-2246H Recombinant Human FGF14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human FGF14-2908H Recombinant Human FGF14 protein, GST-tagged E.coli GST
    Human FGF14-7617H Recombinant Human FGF14, His-tagged E.coli N/A
    Human FGF14-566H Active Recombinant Human FGF14 Protein E.coli N/A
    Mouse Fgf14-2995M Recombinant Mouse Fgf14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse FGF14-5842M Recombinant Mouse FGF14 Protein Mammalian Cell His
    Mouse FGF14-3229M-B Recombinant Mouse FGF14 Protein Pre-coupled Magnetic Beads HEK293
    Mouse FGF14-3229M Recombinant Mouse FGF14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat FGF14-2327R Recombinant Rat FGF14 Protein Mammalian Cell His
    Rat FGF14-1984R-B Recombinant Rat FGF14 Protein Pre-coupled Magnetic Beads HEK293
    Rat FGF14-1984R Recombinant Rat FGF14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Zebrafish FGF14-2036Z Recombinant Zebrafish FGF14 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • FGF14 Related Articles
    • FGF14 Related Research Area
    • FGF14 Related Signal Pathway

    FGF14 involved in several pathways and played different roles in them. We selected most pathways FGF14 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathwayHSP70;MAP3K11;MAPKAPK3;FGF20;FGF14;NFATC1;PLA2G4F;RPS6KA3B;RPS6KA2
    Ras signaling pathwayRGL2;FGF20;FGF10;PIK3R2;PRKCA;PLA2G4F;AKT2;RGL1;Kitl
    Rap signaling pathwayPFN1;PIK3R2;ITGB2L;MAPK1;INS;FGF6;RASSF5;ANGPT2;HGF
    PIK-Akt signaling pathwayGYS1;NFKB1;PCK1;LAMB4;RPTOR;COL6A4;PKN3;FLT1;HGF
    Regulation of actin cytoskeletonITGA8;VCL;PPP1R12C;HRAS;ARHGEF7B;ITGA9;MYL12.1;PPP1R12B;MAP2K2B
    Pathways in cancerPIK3R1;CBLB;ITGA6;BMP4;GLI2;Flt3l;MAPK9;GNG4;GNAI3

    FGF14 has several biochemical functions, for example, NOT fibroblast growth factor receptor binding, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF14 itself. We selected most functions FGF14 had, and list some proteins which have the same functions with FGF14. You can find most of the proteins on our site.

    Function Related Protein
    NOT fibroblast growth factor receptor bindingFGF14;FGF12
    growth factor activityFGF22;CD320;VEGFAA;FGF1;PRL2C3;EREG;NTF4;FGF20A;GDF2

    FGF14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF14 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF14.


    Hsu, WC; Nenov, MN; et al. Identifying a Kinase Network Regulating FGF14:Nav1.6 Complex Assembly Using Split-Luciferase Complementation. PLOS ONE 10:-(2015).
    Yan, HD; Pablo, JL; et al. FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons. ELIFE 3:-(2014).
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