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  • Official Full Name

    fibroblast growth factor 14

  • Overview

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.
  • Synonyms

    FGF14; fibroblast growth factor 14; FHF4; SCA27; MGC119129; MGC129319; bA397O8.2; FHF 4; Fibroblast growth factor homologous factor 4; mFHF-4(1B); MGC129318; RP11-397O8.6; FHF-4; FGF-14;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGF14-566H Active Recombinant Human FGF14 Protein E.coli N/A
Human FGF14-7617H Recombinant Human FGF14, His-tagged E.coli N/A 1-247aa
Human FGF14-6247HCL Recombinant Human FGF14 293 Cell Lysate HEK293 N/A
Human FGF14-6246HCL Recombinant Human FGF14 293 Cell Lysate HEK293 N/A
Human FGF14-028H Recombinant Human FGF14 Protein E. coli
Human FGF14-4104H Recombinant Human FGF14 Protein, GST-tagged Wheat Germ GST
Human FGF14-2908H Recombinant Human FGF14 protein, GST-tagged E.coli GST 1-252aa
Human FGF14-3239H Recombinant Human FGF14 Protein (Met1-Thr252, isoform2), C-His tagged E.coli C-His Met1-Thr252, isoform2
Human FGF14-107H Active Recombinant Human FGF14 Protein (Ala2-Thr246), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala2-Thr246
Human FGF14-2246H Recombinant Human FGF14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse FGF14-5842M Recombinant Mouse FGF14 Protein Mammalian Cell His
Mouse Fgf14-2995M Recombinant Mouse Fgf14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FGF14-3229M-B Recombinant Mouse FGF14 Protein Pre-coupled Magnetic Beads HEK293
Mouse FGF14-3229M Recombinant Mouse FGF14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FGF14-2327R Recombinant Rat FGF14 Protein Mammalian Cell His
Rat FGF14-1984R-B Recombinant Rat FGF14 Protein Pre-coupled Magnetic Beads HEK293
Rat FGF14-1984R Recombinant Rat FGF14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Canine fgf14-169C Active Recombinant Canine fgf14 E.coli N/A Lys64-Thr252
Zebrafish FGF14-2036Z Recombinant Zebrafish FGF14 Mammalian Cell His
Chicken FGF14-6341C Recombinant Chicken FGF14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FGF14 Related Articles
  • FGF14 Related Research Area
  • FGF14 Related Signal Pathway

FGF14 involved in several pathways and played different roles in them. We selected most pathways FGF14 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayPIK3R1;FGF12;PLA2G1B;PRKACG;GNB4;FGF4;GNG10;SHC4;INSR
Regulation of actin cytoskeletonFGF13A;ACTG1;CYFIP2;ITGA10;ARPC4L;PFN2L;MAP2K2B;EZR;WASLB
Pathways in cancerGNG12;CDH1;CCNE2;LPAR5;Fgf15;PTGER4;GNG10;GNGT2;MSH3

FGF14 has several biochemical functions, for example, NOT fibroblast growth factor receptor binding, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF14 itself. We selected most functions FGF14 had, and list some proteins which have the same functions with FGF14. You can find most of the proteins on our site.

Function Related Protein
NOT fibroblast growth factor receptor bindingFGF12;FGF14
growth factor activityGSDF;Pdgfa&Pdgfb;PDGFAB;FGF18A;OSM;LIF;GH1;HBEGF;CTGF

FGF14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF14 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF14.


Hsu, WC; Nenov, MN; et al. Identifying a Kinase Network Regulating FGF14:Nav1.6 Complex Assembly Using Split-Luciferase Complementation. PLOS ONE 10:-(2015).
Yan, HD; Pablo, JL; et al. FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons. ELIFE 3:-(2014).
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