fgf14

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fgf14

Official Full Name fibroblast growth factor 14
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.
Synonyms FGF14; fibroblast growth factor 14; FHF4; SCA27; MGC119129; MGC129319; bA397O8.2; FHF 4; Fibroblast growth factor homologous factor 4; mFHF-4(1B); MGC129318; RP11-397O8.6; FHF-4; FGF-14
    • Species :
    • Canine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF14-4104H Recombinant Human FGF14 Protein, GST-tagged Wheat Germ GST
    Human FGF14-566H Recombinant Human FGF14 Protein E.coli N/A
    Human FGF14-6246HCL Recombinant Human FGF14 293 Cell Lysate HEK293 N/A
    Human FGF14-6247HCL Recombinant Human FGF14 293 Cell Lysate HEK293 N/A
    Human FGF14-7617H Recombinant Human FGF14, His-tagged E.coli N/A
    Mouse FGF14-5842M Recombinant Mouse FGF14 Protein Mammalian Cell His
    Rat FGF14-2327R Recombinant Rat FGF14 Protein Mammalian Cell His
    Canine fgf14-169C Recombinant Canine fgf14 E.coli N/A
    Chicken FGF14-6341C Recombinant Chicken FGF14 Mammalian Cell His
    Zebrafish FGF14-2036Z Recombinant Zebrafish FGF14 Mammalian Cell His

    fgf14 involved in several pathways and played different roles in them. We selected most pathways fgf14 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with fgf14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway ARR3A; ELK1; MAP2K5; MAPK1; GRB2A; RAF1B; MAP4K1; PPP3R2; ARR3B; PRKACAB
    Ras signaling pathway PLA2G6; GAB1; PRKCG; LOC608458; PRKACG; RELA; VEGFC; ETS2; TEK; PIK3R5
    Rap signaling pathway KITLG; RAC2; DOCK4; VEGFA; CALM3; PRKCZ; CDC42; PRKCA; INS1; RAPGEF5
    PIK-Akt signaling pathway IFNA16; PRL; PIK3R5; ITGAV; LAMC2; CD19; HSP90B1; YWHAZ; Kitl; Il4ra
    Regulation of actin cytoskeleton PIK3R1; FGFR1A; PIP4K2C; FGF6B; FGFR3; PAK2; BRAF; ACTB2; GSNA; INSB
    Pathways in cancer FGF7; LAMB1; MSH6; FZD5; LAMC1; PRKACB; FGF14; FGFR1; ERBB2; CCNA1
    Melanoma FGF20; FGF9; IGF1R; FGF2; PDGFB; PIK3R3; FGF3; MDM2; PIK3R1; PDGFA

    fgf14 has several biochemical functions, for example, NOT fibroblast growth factor receptor binding, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fgf14 itself. We selected most functions fgf14 had, and list some proteins which have the same functions with fgf14. You can find most of the proteins on our site.

    Function Related Protein
    NOT fibroblast growth factor receptor binding FGF12; FGF14
    growth factor activity KITLG; INHBC; INHBE; MDKA; FGF11; DKK1; IGF2B; F2; IL9; FGF14
    heparin binding CXCL13; SMOC2; HBEGF; ELANE; RSPO3; SLIT1; EPYC; HDGF; ZNF146; ITGAM

    fgf14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fgf14 here. Most of them are supplied by our site. Hope this information will be useful for your research of fgf14.

    HIST1H3D

    Hsu, WC; Nenov, MN; et al. Identifying a Kinase Network Regulating FGF14:Nav1.6 Complex Assembly Using Split-Luciferase Complementation. PLOS ONE 10:-(2015).
    Yan, HD; Pablo, JL; et al. FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons. ELIFE 3:-(2014).

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