FGF16
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Official Full Name
fibroblast growth factor 16
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Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity, which suggests a role in proliferation of embryonic brown adipose tissue. -
Synonyms
FGF16; fibroblast growth factor 16; FGF-16;
- Involved Pathway
- Protein Function
- Interacting Protein
- FGF16 Related Research Area
- FGF16 Related Signal Pathway
FGF16 involved in several pathways and played different roles in them. We selected most pathways FGF16 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | FLNA;FGF18;MAP2K2;FOS;ATF4B1;CACNA1SB;MAPKAPK2;RPS6KA4;PAK1 |
| Ras signaling pathway | PDGFC;RAB5C;PLD2;RASA4;FLT4;MAPK9;GNG2;PDGFB;SHC2 |
| Rap signaling pathway | BCAR1;FGF21;CDH1;HGF;ITGB1;Fgf15;VAV2;GNAI2;PFN2 |
| PIK-Akt signaling pathway | RPS6KB1;IFNA4;BRCA1;IFNA16;MTCP1;HGF;Il4ra;VEGFB;ITGB4 |
| Regulation of actin cytoskeleton | PPP1R12C;FGF11;INSRR;CFL2;BRK1;ARHGAP35;FGF13A;ITGA11A;ITGB3 |
| Pathways in cancer | FGFR3;AXIN2;BRCA2;GLI3;AXIN1;LAMC1;Fgf15;CASP9;ARNT |
| Melanoma | FGF21;FGF1;PIK3R3;FGFR1;MET;HGF;PDGFRA;PDGFA;FGF10 |
FGF16 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF16 itself. We selected most functions FGF16 had, and list some proteins which have the same functions with FGF16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| fibroblast growth factor receptor binding | FGF3;FGF20;FGF20A;FRS3;FGF1A;FRS2;FGF10A;FGF9;FGF8 |
| growth factor activity | NDP;FGF24;FGF20A;FGF3;IL9;FGF4;VEGFA;FGF13A;Kitl |
FGF16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF16 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF16.
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