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FOXP1

  • Official Full Name

    forkhead box P1

  • Overview

    This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Synonyms

    FOXP1; forkhead box P1; QRF1; 12CC4; hFKH1B; HSPC215; forkhead box protein P1; glutamine-rich factor 1; fork head-related protein like B;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FOXP1-12H Recombinant Human FOXP1 protein, GST-tagged Wheat Germ GST
Human FOXP1-7636H Recombinant Human FOXP1 protein, His & T7-tagged E.coli His/T7 Asn461~Pro671 (Accession # Q9H334)
Human FOXP1-28111TH Recombinant Human FOXP1, His-tagged E.coli His
Human FOXP1-12984H Recombinant Human FOXP1, GST-tagged E.coli GST 349-457a.a.
Human FOXP1-16H Recombinant Human FOXP1 protein, DDK-tagged Insect Cell DDK
Human FOXP1-6146HCL Recombinant Human FOXP1 293 Cell Lysate HEK293 N/A
Human FOXP1-509H Recombinant Human FOXP1 Protein (1-114 aa), GST-tagged E.coli GST 1-114 aa
Human FOXP1-5163H Recombinant Human FOXP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FOXP1-2625H Recombinant Human FOXP1 Protein (Asn461-Pro671), N-His tagged E.coli N-His Asn461-Pro671
Human FOXP1-2447H Recombinant Human FOXP1 protein, His-tagged E.coli His 349-457 aa
Mouse Foxp1-7637M Recombinant Mouse Foxp1 protein, His & T7-tagged E.coli His/T7 Ala122~Asp346 (Accession # P58462)
Mouse FOXP1-6010M Recombinant Mouse FOXP1 Protein Mammalian Cell His
Mouse Foxp1-374M Recombinant Mouse Foxp1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse FOXP1-3337M Recombinant Mouse FOXP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FOXP1-3337M-B Recombinant Mouse FOXP1 Protein Pre-coupled Magnetic Beads HEK293
Rat FOXP1-2388R Recombinant Rat FOXP1 Protein Mammalian Cell His
Rat FOXP1-2044R Recombinant Rat FOXP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FOXP1-2044R-B Recombinant Rat FOXP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FOXP1-1744R Recombinant Rhesus monkey FOXP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FOXP1-1566R-B Recombinant Rhesus Macaque FOXP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FOXP1-1566R Recombinant Rhesus Macaque FOXP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken FOXP1-2197C Recombinant Chicken FOXP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FOXP1 Related Articles
  • FOXP1 Related Research Area

FOXP1 involved in several pathways and played different roles in them. We selected most pathways FOXP1 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MicroRNAs in cancerTHBS1;HOXD10;TGFB2;UBE2I;EP300;NOTCH3;PRKCE;RPTOR;TRP63

FOXP1 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding, androgen receptor binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXP1 itself. We selected most functions FOXP1 had, and list some proteins which have the same functions with FOXP1. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II transcription factor activity, sequence-specific DNA bindingFOXM1;SOX21A;FEV;SOX30;SOX21;TFDP1B;FOXE3;ZNF434;ETV2
androgen receptor bindingWIPI1;CALR;KDM4C;DAXX;PARK7;PRMT2;BRCA1;EP300;Ar
metal ion bindingTSNAX;CYP27C1;Car12;ZFP260;RNASEH2A;SP4;CYP2P7;TNNI1;RPS27L
protein bindingLRRC4C;CYLD;PAK2;ROR2;HTN1;SAC3D1;FGFR1;NXT2;ANLN
sequence-specific DNA bindingPOU4F1;SPI1B;NR2F5;NR1D1;NR1D4B;ENG1A;TFCP2L1;OTPA;RAX2

FOXP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXP1.

LRRK1; IL3RA; alaS; mglA3; q7cia4_yerpe; opuD; ppk; gabD; mdtB; arre2_element_mouse_il2_promoter; MYC

Hu, ZH; Zhu, LC; et al. The expression and correlation between the transcription factor FOXP1 and estrogen receptors in epithelial ovarian cancer. BIOCHIMIE 109C:42-48(2015).
Gringhuis, SI; Kaptein, TM; et al. Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production. NATURE COMMUNICATIONS 5:-(2014).
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