GALC
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Official Full Name
galactocerebroside -
Overview
A galactocerebroside (or galactosylceramide) is a type of cerebroside consisting of a ceramide with a galactose residue at the 1-hydroxyl moiety. -
Synonyms
CERAMIDE BETA-D-GALACTOSIDE;CERAMIDEGALACTOSIDE;Ceramide, 1-O-β-D-galactopyranosyl-;Galactocerebroside;galactocerebroside;galactosylceramide;Galactocerebroside A
Recombinant Proteins
- Human
- Rat
- Rhesus macaque
- Mouse
- E.coli
- CHO
- Mammalian Cells
- HEK293
- Yeast
- In Vitro Cell Free System
- His
- Myc
- Non
- Avi
- Fc
- GST
- Flag
Involved Pathway
GALC involved in several pathways and played different roles in them. We selected most pathways GALC participated on our site, such as Sphingolipid metabolism,Metabolic pathways,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid metabolism | ARSK,CERS4A,DEGS2,NEU1,SERINC1,PPAP2D,LASS2,KDSR,ARSH,GLTPA |
| Metabolic pathways | Amy1,DHODH,RPIA,HMGCL,COX8A,HPSE,TYR,PDHX,GNSB,HMBSB |
| Lysosome | GALCB,SLC11A1,GNS,DNASE2A,CTSK,PLA2G15,CTSSB.2,CTSW,ATP6V1H,PPT2 |
Protein Function
GALC has several biochemical functions, for example, galactosylceramidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALC itself. We selected most functions GALC had, and list some proteins which have the same functions with GALC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| galactosylceramidase activity | GALCA,GALCB |
Interacting Protein
GALC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALC here. Most of them are supplied by our site. Hope this information will be useful for your research of GALC.
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References
- Delmont, E; Halstead, S; et al. Improving the detection of IgM antibodies against glycolipids complexes of GM1 and Galactocerebroside in Multifocal Motor Neuropathy using glycoarray and ELISA assays. JOURNAL OF NEUROIMMUNOLOGY 278:159-161(2015).
- Nobile-Orazio, E; Giannotta, C; et al. Sensitivity and predictive value of anti-GM1/galactocerebroside IgM antibodies in multifocal motor neuropathy. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 85:754-758(2014).
