"GALC" Related Products

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Recombinant Human GALC Protein, His-tagged

Cat.No.: GALC-528H
Product Overview: Recombinant Human GALC(Asp375~Asn535) fused with His tag at N-terminal was expressed in E. coli.
Description: This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Source: E. coli
Species: Human
Tag : His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 20.1kDa
Protein length: Asp375~Asn535
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 98%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: GALC galactosylceramidase [ Homo sapiens ]
Official Symbol: GALC
Synonyms: GALC; galactosylceramidase; galactosylceramidase (Krabbe disease); galactocerebrosidase; Krabbe disease; GALCERase; galactosylceraminidase; galactocerebroside beta-galactosidase; galactosylceramide beta-galactosidase;
Gene ID: 2581
mRNA Refseq: NM_000153
Protein Refseq: NP_000144
MIM: 606890
UniProt ID: P54803

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