GHSR Protein

GHSR

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GHSR

Official Full Name growth hormone secretagogue receptor
Background This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Synonyms GHSR; growth hormone secretagogue receptor; growth hormone secretagogue receptor type 1; GH releasing peptide receptor; GH-releasing peptide receptor; Ghrelin receptor; GHRP; GHRPR; GHS-R; GHSR_HUMAN; Growth hormone secretagogue receptor 1; growth hormone secretatgogue receptor
    • Species :
    • Chicken
    • Homo sapiens (Human)
    • Human
    • Mus musculus (Mouse)
    • Mustela putorius furo (European domestic ferret) (Mustela furo)
    • Oryctolagus cuniculus (Rabbit)
    • Rat
    • Rattus norvegicus (Rat)
    • Sus scrofa (Pig)
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His&Flag
    • N/A
    • N-His&GST
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GHSR-29024TH Recombinant Human GHSR Wheat Germ N/A Inquiry
    Rat GHSR-2532R Recombinant Rat GHSR Protein Mammalian Cell His Inquiry
    Chicken GHSR-5964C Recombinant Chicken GHSR Mammalian Cell His Inquiry
    Human GHSR-1043HFL Recombinant Human GHSR protein, His&Flag-tagged HEK293 His&Flag Inquiry
    Human GHSR-1578H Recombinant Human GHSR Protein, His&GST-tagged E.coli N-His&GST Inquiry
    Human GHSR-197HF Recombinant Full Length Human GHSR Protein In Vitro Cell Free System Inquiry
    Human GHSR-5254HF Recombinant Full Length Human GHSR Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Homo sapiens (Human) RFL12638HF Recombinant Full Length Human Growth Hormone Secretagogue Receptor Type 1(Ghsr) Protein, His-Tagged E.coli expression system His Inquiry
    Mus musculus (Mouse) RFL17486MF Recombinant Full Length Mouse Growth Hormone Secretagogue Receptor Type 1(Ghsr) Protein, His-Tagged E.coli expression system His Inquiry
    Oryctolagus cuniculus (Rabbit) RFL2283OF Recombinant Full Length Rabbit Growth Hormone Secretagogue Receptor Type 1(Ghsr) Protein, His-Tagged E.coli expression system His Inquiry
    Sus scrofa (Pig) RFL32854SF Recombinant Full Length Pig Growth Hormone Secretagogue Receptor Type 1(Ghsr) Protein, His-Tagged E.coli expression system His Inquiry
    Rattus norvegicus (Rat) RFL6718RF Recombinant Full Length Rat Growth Hormone Secretagogue Receptor Type 1(Ghsr) Protein, His-Tagged E.coli expression system His Inquiry
    Mustela putorius furo (European domestic ferret) (Mustela furo) RFL9735MF Recombinant Full Length Mustela Putorius Furo Growth Hormone Secretagogue Receptor Type 1(Ghsr) Protein, His-Tagged E.coli expression system His Inquiry
    Human GHSR-4895H Recombinant Human GHSR Protein, GST-tagged Wheat Germ GST Inquiry
    Kit-0904 TR-FRET PXR (SXR) Competitive Binding Assay Kit, goat N/A Inquiry
    Kit-1255 GHSR U2OS β-Arrestin-1 GPCR Assay Kit N/A Inquiry

    GHSR involved in several pathways and played different roles in them. We selected most pathways GHSR participated on our site, such as cAMP signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GHSR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cAMP signaling pathway CNGA3; GRIA1; PPARA; PPP1CA; GABBR1; CALM3; SLC9A1; PIK3R1; ATP1A3; RAC1
    Neuroactive ligand-receptor interaction HRH1; VIPR2; CCKBR; SCTR; PTGER4A; TAAR13E; CHRNA2A; GHRHRL; GRIA2B; TAAR7B

    GHSR has several biochemical functions, for example, G-protein coupled receptor activity, growth hormone secretagogue receptor activity, growth hormone-releasing hormone receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GHSR itself. We selected most functions GHSR had, and list some proteins which have the same functions with GHSR. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity MRGPRA8; TAS1R2.2; SETD6; FZD8A; MRGPRB8; OR8A1; GPR125; OLFR149; RGS1; CALCRLA
    growth hormone secretagogue receptor activity GHSR
    growth hormone-releasing hormone receptor activity GHSR; GHRHR; MLNR; GHRHRA; GHSRA
    peptide hormone binding PTH1RA; GALR2; GHSR; RXFP2; GALR1; GHR; NPR2; AGTR1B; MAS1; HCRTR1

    GHSR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GHSR here. Most of them are supplied by our site. Hope this information will be useful for your research of GHSR.

    Mani, BK; Walker, AK; et al. Neuroanatomical Characterization of a Growth Hormone Secretagogue Receptor-Green Fluorescent Protein Reporter Mouse. JOURNAL OF COMPARATIVE NEUROLOGY 522:3644-3666(2014).
    Niarami, MD; Masoudi, AA; et al. ASSOCIATION OF SINGLE NUCLEOTIDE POLYMORPHISM OF GHSR AND TGFB2 GENES WITH GROWTH AND BODY COMPOSITION TRAITS IN SIRE AND DAM LINES OF A BROILER CHICKEN. ANIMAL BIOTECHNOLOGY 25:13-22(2014).

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