GK
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Official Full Name
Glycerol Kinase
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Overview
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway. NB - Glycerol kinase obtained from Cellulomonas spp has an observed molecular weight of 128kDa. Glycerol kinase is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis -
Synonyms
ATP glycerol 3 phosphotransferase; ATP:glycerol 3 phosphotransferase; ATP:glycerol 3-phosphotransferase; GK; GK1; GKD; GLPK; Glycerokinase; Glycerol kinase; Glycerol kinase deficiency; OTTHUMP00000023108; OTTHUMP00000023109; OTTHUMP00000215321; D930012N15Rik;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- E. coli
- Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus)
- Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)
- Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1)
- Human
- Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
- Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)
- Human herpesvirus 1 (strain MP) (HHV-1) (Human herpes simplex virus 1)
- Human herpesvirus 1 (strain R15) (HHV-1) (Human herpes simplex virus 1)
- Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2)
- Mouse
- Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus)
- Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))
- Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
- Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)
- E. coli
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | GK-13284H | Recombinant Human GK, GST-tagged | E.coli | GST | 1-357a.a. | |
| Human | GK-414H | Recombinant Human GK | Mammalian Cell | His |
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| Human | GK-29028TH | Recombinant Human GK | Wheat Germ | N/A | 93 amino acids |
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| Human | GK-5914HCL | Recombinant Human GK 293 Cell Lysate | HEK293 | N/A |
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| Human | GK-5913HCL | Recombinant Human GK 293 Cell Lysate | HEK293 | N/A |
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| Human | GK-4805H | Recombinant Human GK Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | GK-3037H-B | Recombinant Human GK Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | GK-4936H | Recombinant Human GK Protein, GST-tagged | Wheat Germ | GST |
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| Human | GK-3037H | Recombinant Human GK Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Human | GK-4308H | Recombinant Human GK Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | GK-3238H | Recombinant Human GK protein, His-tagged | E.coli | His | 1-357 aa | |
| Human | GK-5300HF | Recombinant Full Length Human GK Protein, GST-tagged | In Vitro Cell Free System | GST | 524 amino acids |
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| Mouse | Gk-1081M | Recombinant Mouse Gk Protein, MYC/DDK-tagged | HEK293T | MYC/DDK |
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| E. coli | GK-332E | Active Recombinant E. coli Glycerol Kinase Protein, His-tagged | E. coli | His | Met1-Glu502 |
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| Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) | RFL17628EF | Recombinant Full Length Equine Herpesvirus 1 Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (32-343) |
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| Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus) | RFL19015EF | Recombinant Full Length Equine Herpesvirus 1 Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (32-343) |
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| Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) | RFL5054GF | Recombinant Full Length Gallid Herpesvirus 2 Glycoprotein K(Mdv067) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (32-354) |
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| Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) | RFL23251HF | Recombinant Full Length Human Herpesvirus 1 Envelope Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (31-338) |
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| Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1) | RFL16696HF | Recombinant Full Length Human Herpesvirus 1 Envelope Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (31-338) |
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| Human herpesvirus 1 (strain MP) (HHV-1) (Human herpes simplex virus 1) | RFL25393HF | Recombinant Full Length Human Herpesvirus 1 Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length (31-338) |
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| Human herpesvirus 1 (strain R15) (HHV-1) (Human herpes simplex virus 1) | RFL30236HF | Recombinant Full Length Human Herpesvirus 1 Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length (31-338) |
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| Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) | RFL15952HF | Recombinant Full Length Human Herpesvirus 2 Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length (31-338) |
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| Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) | RFL33923PF | Recombinant Full Length Psittacid Herpesvirus 1 Glycoprotein K(Ul53) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (34-358) |
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| Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan)) | RFL33742SF | Recombinant Full Length Suid Herpesvirus 1 Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length (21-312) |
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| Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) | RFL6954VF | Recombinant Full Length Varicella-Zoster Virus Envelope Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (22-340) |
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| Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3) | RFL32787VF | Recombinant Full Length Varicella-Zoster Virus Glycoprotein K(Gk) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (22-340) |
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- Involved Pathway
- Protein Function
- Interacting Protein
- GK Related Articles
GK involved in several pathways and played different roles in them. We selected most pathways GK participated on our site, such as Glycerolipid metabolism, Metabolic pathways, PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | AGK;ALDH2;PPAP2C;LPIN1;MBOAT2B;MOGAT1;AKR1B8;STIL;AGPAT1 |
| Metabolic pathways | OXSM;BAAT;DGKZ;HLCS;HPSE2;FUT8A;LIPT1;DCT;CYP2J5 |
| PPAR signaling pathway | ACAA1A;PLTP;ACSL3A;SLC27A1A;SLC27A1B;PDPK1;PPARAB;RXRGB;RXRA |
GK has several biochemical functions, for example, ATP binding, glycerol kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GK itself. We selected most functions GK had, and list some proteins which have the same functions with GK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | WRN;CDK19;PRKCDA;HK1;PSKH2;CDC42BPG;COASY;PGK2;RECQL4 |
| glycerol kinase activity | GK2;GK5;GK |
| protein binding | GPRASP1;VTA1;FBLIM1;CASP8;CMKLR1;CSNK1G1;MAGEE1;GPA33;CDK1 |
GK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GK here. Most of them are supplied by our site. Hope this information will be useful for your research of GK.
Sicurella, M; Nicoli, F; et al. An Attenuated Herpes Simplex Virus Type 1 (HSV1) Encoding the HIV-1 Tat Protein Protects Mice from a Deadly Mucosal HSV1 Challenge. PLOS ONE 9:-(2014).
Jambunathan, N; Chouljenko, D; et al. Herpes Simplex Virus 1 Protein UL37 Interacts with Viral Glycoprotein gK and Membrane Protein UL20 and Functions in Cytoplasmic Virion Envelopment. JOURNAL OF VIROLOGY 88:5927-5935(2014).
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