Recombinant Human GK, GST-tagged

• Cat.No.: GK-13284H
• Product Overview: Recombinant Human GK protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-357a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GK glycerol kinase [ Homo sapiens ]
• Official Symbol: GK
• Synonyms: glycerol kinase; 4289; Ensembl:ENSG00000198814; glycerol kinase;glycerokinase;ATP:glycerol 3-phosphotransferase; 2.7.1.30; GK1; GKD
• Gene ID: 2710
• mRNA Refseq: NM_000167.5
• Protein Refseq: NP_000158.1
• MIM: 300474
• UniProt ID: B4DH54
• Chromosome Location: Xp21.3
• Pathway: Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; Glycerolipid metabolism, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem
• Function: ATP binding; glycerol kinase activity; glycerol kinase activity; protein binding