GNAQ

  • Official Full Name

    guanine nucleotide binding protein (G protein), q polypeptide
  • Overview

    This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010]
  • Synonyms

    GNAQ;guanine nucleotide binding protein (G protein), q polypeptide;GAQ;SWS;CMC1;G-ALPHA-q;guanine nucleotide-binding protein G(q) subunit alpha;guanine nucleotide-binding protein alpha-q

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Chicken
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cells
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • DDK
  • Myc
  • Non
  • Flag
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GNAQ-13350H Recombinant Human GNAQ protein, GST-tagged E.coli Human GST 84-205 aa
GNAQ-8728H Recombinant Human GNAQ, His-tagged E.coli Human His 1-359aa
GNAQ-02H Recombinant Human GNAQ Protein, Myc/DDK-tagged HEK293 Human DDK&Myc
GNAQ-1894R Recombinant Rhesus monkey GNAQ Protein, His-tagged Mammalian Cells Rhesus macaque His
GNAQ-2597R Recombinant Rat GNAQ Protein Mammalian Cells Rat His
GNAQ-3076C Recombinant Chicken GNAQ Mammalian Cells Chicken His
GNAQ-7019M Recombinant Mouse GNAQ Protein Mammalian Cells Mouse His
GNAQ-7289Z Recombinant Zebrafish GNAQ Mammalian Cells Zebrafish His
GNAQ-5867HCL Recombinant Human GNAQ 293 Cell Lysate HEK293 Human Non
GNAQ-1109HFL Recombinant Full Length Human GNAQ Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
GNAQ-1714R Recombinant Rhesus Macaque GNAQ Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
GNAQ-1714R-B Recombinant Rhesus Macaque GNAQ Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GNAQ-2252R Recombinant Rat GNAQ Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GNAQ-2252R-B Recombinant Rat GNAQ Protein Pre-coupled Magnetic Beads HEK293 Rat
GNAQ-2585M Recombinant Mouse GNAQ Protein (1-359 aa), His-Myc-tagged E.coli Mouse His&Myc 1-359 aa
Gnaq-3258M Recombinant Mouse Gnaq Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
GNAQ-32H Recombinant Human GNAQ Protein, His-tagged E.coli Human His
GNAQ-3761M Recombinant Mouse GNAQ Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
GNAQ-3761M-B Recombinant Mouse GNAQ Protein Pre-coupled Magnetic Beads HEK293 Mouse
GNAQ-5046H Recombinant Human GNAQ Protein, GST-tagged Wheat Germ Human GST
GNAQ-5328HF Recombinant Full Length Human GNAQ Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 359 amino acids
GNAQ-5831H Recombinant Human GNAQ Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
GNAQ-998H Recombinant Human GNAQ Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
GNAQ-998H-B Recombinant Human GNAQ Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    GNAQ involved in several pathways and played different roles in them. We selected most pathways GNAQ participated on our site, such as Rap signaling pathway,Calcium signaling pathway,cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNAQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alzheimers disease ATP5C1,COX6A2,NDUFC2-KCTD14,PPP3CB,HSD17B10,NDUFS2,PLCB1,ATP5H,COX7A1,COX4I2
    Chagas disease (American trypanosomiasis) C1QB,AKT1,CCL3L1,PLCB4,PPP2R2A,IFNB1,IKBKG,TGFBR1,AKT2,GNAI2
    Endocrine and other factor-regulated calcium reabsorption RAB11A,VDR,PLCB3,KLK1B8,KLK1B9,ATP1A4,PRKACB,ATP1A2,PRKCA,ATP1B4
    Dopaminergic synapse CAMK2A,PPP2R2A,GNG2,DRD1,CALY,DRD2,AKT2,PPP2R5B,GNG4,CALM4
    Vascular smooth muscle contraction PLA2G2E,CACNA1DA,PRKG1A,PRKCH,RAF1B,KCNMB2,RHOAB,NPR1,PPP1CC,MYLK
    Serotonergic synapse ALOX5,PLA2G4A,MAP2K1,HTR3A,SLC18A1,CYP2D9,PTGS1,HTR4,HTR2C,CYP2C37
    Pancreatic secretion AMY2A,ATP2A2,CELA2A,PLCB3,PLCB1,PLA2G3,PRKCB,RAP1B,CLCA2,PLCB2
    Pathways in cancer F2R,GNG12,CCDC6,BIRC2,BAX,FZD10,AKT2,GNG11,AXIN2,LAMA2
    cGMP-PKG signaling pathway ATP1A2,NPPB,MEF2D,AGTR1A,PIK3CG,PIK3CA,SLC25A6,KCNMB3,ATP2B4,CALM3

    Protein Function

    GNAQ has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,GTP binding,GTPase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNAQ itself. We selected most functions GNAQ had, and list some proteins which have the same functions with GNAQ. You can find most of the proteins on our site.

    Function Related Protein
    protein binding NAE1,EYA4,PPP2R5A,TAPBP,RPUSD4,CBX8,KCNA1,DNMT1,TIMM8A,TBC1D9B
    type 2A serotonin receptor binding GNA11,ARRB2
    G-protein beta/gamma-subunit complex binding GNAI1,Adcy4,GNAO1B,GNAS,GNA12,CETN1,GNA14,GNA12A,ADORA1,GNA15.4
    GTP binding GNA13,EIF5B,RAP2B,RHOAA,RAB1B,SRP54A,ARL17B,SEPT10,ARF4A,GNL1
    GTPase activator activity CHML,AGAP5,RINL,RASA4,ASAP2,RGS17,STARD13,TBC1D21,ACAP2,TBC1D16
    signal transducer activity GNG3,CC2D1A,GNA12A,PTK2,GNAS,DRD2B,MIER1,TAS2R110,TAS2R121,GNA13B
    metal ion binding MOCS1,COPS5,ZFYVE16,HPDA,ME3,RFWD2,ZSCAN4F,TSNAX,ICN,HPDB
    GTPase activity DNM1L,MX2,TUBA1B,MXB,RRAGCB,RAB21,RAB11A,ARHGDIB,GBP5,ARL4D

    Interacting Protein

    GNAQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNAQ here. Most of them are supplied by our site. Hope this information will be useful for your research of GNAQ.

    RARA;ARRB1;PARP2;PECAM1;AGTR1;CXCR5;PPT1;LUM;ADHFE1;NT5C3A;pi3p;FLOT2;Myh10

    Resources

    References

    Ask a Question for All GNAQ Products

    Required fields are marked with *

    My Review for All GNAQ Products

    Required fields are marked with *