Human GNAQ Knockdown Cell Lysate

• Cat.No.: GNAQ-178HKCL
• Product Overview: WB-validated GNAQ Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 42 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg GNAQ KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Long-term depression, Long-term potentiation, Melanogenesis, Vascular smooth muscle contraction
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: GNAQ guanine nucleotide binding protein (G protein), q polypeptide [ Homo sapiens (human) ]
• Official Symbol: GNAQ
• Synonyms: GNAQ; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide-binding protein G(q) subunit alpha; G ALPHA q; GAQ; guanine nucleotide-binding protein alpha-q; G-ALPHA-q
• Gene ID: 2776
• mRNA Refseq: NM_002072
• Protein Refseq: NP_002063
• MIM: 600998
• UniProt ID: P50148