Recombinant Human GNAQ Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GNAQ-5831H
• Product Overview: GNAQ MS Standard C13 and N15-labeled recombinant protein (NP_002063) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 42.1 kDa
• AA Sequence: MTLESIMACCLSEEAKEARRINDEI ERQLRRDKRDARRELKLLLLGTGES GKSTFIKQMRIIHGSGYSDEDKRGF TKLVYQNIFTAMQAMIRAMDTLKIP YKYEHNKAHAQLVREVDVEKVSAFE NPYVDAIKSLWNDPGIQECYDRRRE YQLSDSTKYYLNDLDRVADPAYLPT QQDVLRVRVPTTGIIEYPFDLQSVI FRMVDVGGQRSERRKWIHCFENVTS IMFLVALSEYDQVLVESDNENRMEE SKALFRTIITYPWFQNSSVILFLNK KDLLEEKIMYSHLVDYFPEYDGPQR DAQAAREFILKMFVDLNPDSDKIIY SHFTCATDTENIRFVFAAVKDTILQ LNLKEYNLVTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GNAQ G protein subunit alpha q [ Homo sapiens (human) ]
• Official Symbol: GNAQ
• Synonyms: GNAQ; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide-binding protein G(q) subunit alpha; G ALPHA q; GAQ; guanine nucleotide-binding protein alpha-q; G-ALPHA-q
• Gene ID: 2776
• mRNA Refseq: NM_002072
• Protein Refseq: NP_002063
• MIM: 600998
• UniProt ID: P50148