GRIA3

  • Official Full Name

    Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3)
  • Synonyms

    GRIA3;glutamate receptor, ionotropic, AMPA3 (alpha 3);glutamate receptor 3;glutamate receptor subunit 3;AMPA-selective glutamate receptor 3;glutamate receptor ionotropic, AMPA 3;glutamate receptor channel alpha3 subunit;GluA3;Glur3;GluR-C;Glur-3;GluR-K3;mKIAA4184;Gluralpha3;2900064I19Rik;KIAA4184

Recombinant Proteins

  • Human
  • Rat
  • Chicken
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • Yeast
  • HEK293
  • In Vitro Cell Free System
  • His
  • T7
  • Non
  • Avi
  • Fc
  • GST
  • SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
GRIA3-1352H Recombinant Human GRIA3 protein, His & T7-tagged E.coli Human His&T7 Thr649~Asn823
GRIA3-2691R Recombinant Rat GRIA3 Protein Mammalian Cells Rat His
GRIA3-27524TH Recombinant Human GRIA3 Wheat Germ Human Non 100 amino acids
GRIA3-3793C Recombinant Chicken GRIA3 Mammalian Cells Chicken His
GRIA3-6768C Recombinant Chicken GRIA3 Mammalian Cells Chicken His
GRIA3-752HCL Recombinant Human GRIA3 cell lysate Human Non
GRIA3-1405H Recombinant Human GRIA3 Protein (151-250 aa), His-tagged Yeast Human His 151-250 aa
GRIA3-2345R Recombinant Rat GRIA3 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GRIA3-2345R-B Recombinant Rat GRIA3 Protein Pre-coupled Magnetic Beads HEK293 Rat
GRIA3-2761H Recombinant Human GRIA3 protein(741-810 aa), C-His-tagged E.coli Human His 741-810 aa
GRIA3-5331H Recombinant Human GRIA3 Protein, GST-tagged Wheat Germ Human GST
GRIA3-537H Recombinant Human GRIA3 Protein (151-250 aa), His-SUMO-tagged E.coli Human His&SUMO 151-250 aa
GRIA3-5622HF Recombinant Full Length Human GRIA3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 144 amino acids

    Involved Pathway

    GRIA3 involved in several pathways and played different roles in them. We selected most pathways GRIA3 participated on our site, such as cAMP signaling pathway,Neuroactive ligand-receptor interaction,Circadian entrainment, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction NPFFR1L3,NPFFR2,THRB,GABRR1,FPR3,HTR5AL,GRM4,NPY6R,GABRA1,GNRHR4
    Circadian entrainment GNAS,GRIN2C,RYR2,KCNJ9,CALM3,GNAI2,PLCB4,GUCY1A3,PRKCG,MAPK3
    cAMP signaling pathway PLD2,HCAR2,GRIA4,NFKBIA,PIK3CD,ATP1A2,ROCK1,MAPK9,CREB5,CAMK2G
    Dopaminergic synapse CAMK2G,GNB2,GNAI2,CALM2,MAPK13,PPP2R5B,AKT2,PPP1CB,SLC6A3,GNGT1
    Transcriptional misregulation in cancer ETV6,Pdgfa&Pdgfb,PDGFA,HIST2H3A,ETV4,RELA,MMP3,TAF15,SP1,EWSR1
    Nicotine addiction GRIA4,GABRA4,GABRG3,GRIN2C,GRIN3B,GABRB1,GABRA5,SLC17A8,GRIN1,GABRR2
    Long-term depression GNAZ,GRM1,CRH,PLCB3,GNA12,GNA13,MAPK3,RYR1,PLA2G4D,GUCY1B3
    Glutamatergic synapse PLA2G4D,GRIA4,GRM2,GRIN3B,SHANK1,GRIN2C,SLC1A6,HOMER1,PLCB2,SLC1A1
    Retrograde endocannabinoid signaling ITPR3,GRIA2,GNG4,GNG3,GABRA6,GABRB2,Adcy4,GABRA4,SLC17A7,ITPR1

    Protein Function

    GRIA3 has several biochemical functions, for example, AMPA glutamate receptor activity,extracellular-glutamate-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIA3 itself. We selected most functions GRIA3 had, and list some proteins which have the same functions with GRIA3. You can find most of the proteins on our site.

    Function Related Protein
    extracellular-glutamate-gated ion channel activity GRIN3A,GRIA4,GRIA3A,GRIA1,GRIK5,GRIN1A,GRIA3B,GRIK2,GRIN1,GRIA2A
    AMPA glutamate receptor activity GRIA1B,GRIA2A,GRIA2,GRIA4B,GRIA1A,GRIA2B,GRIA3A,GRIA4,GRIA4A,GRIA3B

    Interacting Protein

    GRIA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIA3.

    Resources

    References

    • Xie, YJ; Tang, W; et al. Microduplication of chromosome Xq25 encompassing STAG2 gene in a boy with intellectual disability. EUROPEAN JOURNAL OF MEDICAL GENETICS 58:116-121(2015).
    • Priya, A; Johar, K; et al. Nuclear respiratory factor 2 regulates the transcription of AMPA receptor subunit GluA2 (Gria2). BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1843:3018-3028(2014).

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