GRIA3
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Official Full Name
Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) -
Synonyms
GRIA3;glutamate receptor, ionotropic, AMPA3 (alpha 3);glutamate receptor 3;glutamate receptor subunit 3;AMPA-selective glutamate receptor 3;glutamate receptor ionotropic, AMPA 3;glutamate receptor channel alpha3 subunit;GluA3;Glur3;GluR-C;Glur-3;GluR-K3;mKIAA4184;Gluralpha3;2900064I19Rik;KIAA4184
Recombinant Proteins
- Human
- Rat
- Chicken
- E.coli
- Mammalian Cells
- Wheat Germ
- Yeast
- HEK293
- In Vitro Cell Free System
- His
- T7
- Non
- Avi
- Fc
- GST
- SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GRIA3-1352H | Recombinant Human GRIA3 protein, His & T7-tagged | E.coli | Human | His&T7 | Thr649~Asn823 |
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| GRIA3-2691R | Recombinant Rat GRIA3 Protein | Mammalian Cells | Rat | His |
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| GRIA3-27524TH | Recombinant Human GRIA3 | Wheat Germ | Human | Non | 100 amino acids |
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| GRIA3-3793C | Recombinant Chicken GRIA3 | Mammalian Cells | Chicken | His |
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| GRIA3-6768C | Recombinant Chicken GRIA3 | Mammalian Cells | Chicken | His |
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| GRIA3-752HCL | Recombinant Human GRIA3 cell lysate | Human | Non |
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| GRIA3-1405H | Recombinant Human GRIA3 Protein (151-250 aa), His-tagged | Yeast | Human | His | 151-250 aa |
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| GRIA3-2345R | Recombinant Rat GRIA3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| GRIA3-2345R-B | Recombinant Rat GRIA3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GRIA3-2761H | Recombinant Human GRIA3 protein(741-810 aa), C-His-tagged | E.coli | Human | His | 741-810 aa |
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| GRIA3-5331H | Recombinant Human GRIA3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GRIA3-537H | Recombinant Human GRIA3 Protein (151-250 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 151-250 aa |
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| GRIA3-5622HF | Recombinant Full Length Human GRIA3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 144 amino acids |
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Involved Pathway
GRIA3 involved in several pathways and played different roles in them. We selected most pathways GRIA3 participated on our site, such as cAMP signaling pathway,Neuroactive ligand-receptor interaction,Circadian entrainment, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | PROM1,IL-8,NFKBIZ,BCL2L1,SIX4,IL3,CEBPE,SS18,CLSTN2,PRCC |
| Glutamatergic synapse | GRIN2B,SHANK2,TRPC1,PRKCA,GRIN2D,GNG5,PLCB1,PLCB4,GNGT2,SLC17A8 |
| Circadian entrainment | KCNJ5,PER2,GNAQ,KCNJ6,NOS1AP,RYR2,GNAI2,GRIA4,PRKACB,CALML5 |
| Nicotine addiction | SLC17A6,GABRA3,GABRA4,GRIN2B,GABRE,GRIN2A,GABRB3,GABRR1,GRIN2D,GABRG2 |
| Dopaminergic synapse | DDC,CREB3,KIF5C,CAMK2B,SLC18A2,GNB4,CREB3L1,KCNJ3,PRKCG,GNGT1 |
| cAMP signaling pathway | GRIN2A,PPP1CB,PIK3CG,GIPR,GNAI2,GRIA1,NFKBIA,NPY,LOC100328615,PRKACG |
| Retrograde endocannabinoid signaling | MAPK13,GNAI3,GNG11,SLC17A7,GNG2,GNGT2,GNB2,GABRA3,MAPK8,GNG4 |
| Long-term depression | GNAQ,GNAZ,MAPK1,IGF1R,RYR1,LYN,GNAS,MAPK3,PRKG2,PLA2G4C |
| Neuroactive ligand-receptor interaction | LEPR,DRD7,TRHR2,TAAR10C,TAAR12G,CHRNA2,GRIA3A,LPAR4,P2RY14,TAAR10B |
Protein Function
GRIA3 has several biochemical functions, for example, AMPA glutamate receptor activity,extracellular-glutamate-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIA3 itself. We selected most functions GRIA3 had, and list some proteins which have the same functions with GRIA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| AMPA glutamate receptor activity | GRIA3A,GRIA2A,GRIA2B,GRIA1B,GRIA4,GRIA1,GRIA1A,GRIA2,GRIA4A,GRIA4B |
| extracellular-glutamate-gated ion channel activity | GRIK2,GRIA4B,GRIA1A,GRIN2B,GRIA2A,GRIN3B,GRIN2C,GRIA1B,GRIK5,GRIN1B |
Interacting Protein
GRIA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIA3.
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References
- Xie, YJ; Tang, W; et al. Microduplication of chromosome Xq25 encompassing STAG2 gene in a boy with intellectual disability. EUROPEAN JOURNAL OF MEDICAL GENETICS 58:116-121(2015).
- Priya, A; Johar, K; et al. Nuclear respiratory factor 2 regulates the transcription of AMPA receptor subunit GluA2 (Gria2). BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1843:3018-3028(2014).
