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Recombinant Human GRIA3 Protein (151-250 aa), His-tagged

Cat.No. : GRIA3-1405H
Product Overview : Recombinant Human GRIA3 Protein (151-250 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial.
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  • Gene Information
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Description : Receptor for glutamate that functions as ligand-gated ion channel in the central nervous syst and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous syst. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 14.0 kDa
Protein length : 151-250 aa
AA Sequence : SLLGHYKWEKFVYLYDTERGFSILQ AIMEAAVQNNWQVTARSVGNIKDVQ EFRRIIEEMDRRQEKRYLIDCEVER INTILEQVVILGKHSRGYHYMLANL
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : GRIA3 glutamate receptor, ionotropic, AMPA 3 [ Homo sapiens ]
Official Symbol : GRIA3
Synonyms : GRIA3; GluA3; GLURC; MRX94; gluR-3; dJ1171F9.1; GLUR3; GLUR-C; GLUR-K3;
Gene ID : 2892
mRNA Refseq : NM_000828
Protein Refseq : NP_000819
MIM : 305915
UniProt ID : P42263

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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