Recombinant Human GRIA3 Protein (151-250 aa), His-SUMO-tagged
| Cat.No. : | GRIA3-537H |
| Product Overview : | Recombinant Human GRIA3 Protein (151-250 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His&SUMO |
| Protein Length : | 151-250 aa |
| Description : | Receptor for glutamate that functions as ligand-gated ion channel in the central nervous syst and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous syst. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
| Form : | Tris-based buffer, 50% glycerol |
| Molecular Mass : | 28.0 kDa |
| AA Sequence : | SLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
| Gene Name | GRIA3 glutamate receptor, ionotropic, AMPA 3 [ Homo sapiens ] |
| Official Symbol | GRIA3 |
| Synonyms | GRIA3; GluA3; GLURC; MRX94; gluR-3; dJ1171F9.1; GLUR3; GLUR-C; GLUR-K3; |
| Gene ID | 2892 |
| mRNA Refseq | NM_000828 |
| Protein Refseq | NP_000819 |
| MIM | 305915 |
| UniProt ID | P42263 |
Not For Human Consumption!
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