• Official Full Name

    hypoxia inducible factor 1, alpha subunit inhibitor

  • Overview

    Hypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene.
  • Synonyms

    HIF1AN; hypoxia inducible factor 1, alpha subunit inhibitor; hypoxia-inducible factor 1-alpha inhibitor; DKFZp762F1811; FIH1; FLJ20615; FLJ22027; Peptide aspartate beta dioxygenase; FIH-1; factor inhibiting HIF1; factor inhibiting HIF-1; peptide-aspartate;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HIF1AN-29315TH Recombinant Human HIF1AN E.coli N/A
Human HIF1AN-5022H Recombinant Human Hypoxia Inducible Factor 1, Alpha Subunit Inhibitor Human N/A
Human HIF1AN-4748H Recombinant Human HIF1AN Protein, GST-tagged Wheat Germ GST
Human HIF1AN-361H Recombinant Human Hypoxia-Inducible Factor 1, Alpha Subunit Inhibitor E.coli N/A
Human HIF1AN-249H Recombinant Human HIF1AN Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HIF1AN-5564HCL Recombinant Human HIF1AN 293 Cell Lysate HEK293 N/A
Human HIF1AN-448H Recombinant Human HIF1AN Protein, His-tagged E.coli His
Human HIF1AN-1069H Recombinant Human HIF1AN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HIF1AN-30176H Recombinant Human HIF1AN protein, GST-tagged E.coli GST
Human HIF1AN-1402HFL Recombinant Full Length Human HIF1AN Protein, C-Flag-tagged Mammalian cells Flag
Human HIF1AN-3038H Recombinant Human HIF1AN protein, His-tagged E.coli His
Human HIF1AN-3467HF Recombinant Full Length Human HIF1AN Protein, GST-tagged In Vitro Cell Free System GST
Human HIF1AN-3560H Recombinant Human HIF1AN Protein (Ala2-Asn349), His tagged E.coli His
Human HIF1AN-1069H-B Recombinant Human HIF1AN Protein Pre-coupled Magnetic Beads HEK293
Mouse HIF1AN-7623M Recombinant Mouse HIF1AN Protein Mammalian Cell His
Mouse HIF1AN-4162M Recombinant Mouse HIF1AN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hif1an-3394M Recombinant Mouse Hif1an Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HIF1AN-4162M-B Recombinant Mouse HIF1AN Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HIF1AN-11541Z Recombinant Zebrafish HIF1AN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HIF1AN Related Articles
  • HIF1AN Related Research Area

HIF1AN involved in several pathways and played different roles in them. We selected most pathways HIF1AN participated on our site, such as Cellular response to hypoxia, Cellular responses to stress, HIF-2-alpha transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIF1AN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cellular response to hypoxiaHIF1AL;EGLN1B;EPAS1B;EGLN3;HIF3A;EGLN2;HIF1AN
Cellular responses to stressRAD50;WDR45;HSBP1B;EGLN1B;CDKN2B;HMGA1;HSPA7;MINK1;WIPI2
HIF-2-alpha transcription factor networkEGLN2;CITED2;EGLN3;HIF1AN
Hypoxic and oxygen homeostasis regulation of HIF-1-alphaHIF1AN;HIF3A;COPS5;GNB2L1;NAA10
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor AlphaEPAS1B;HIF1AN
Regulation of Hypoxia-inducible Factor (HIF) by oxygenEGLN1B;HIF1AN;HIF1AL;EPAS1B;HIF3A;EGLN3;EGLN2

HIF1AN has several biochemical functions, for example, NF-kappaB binding, Notch binding, ankyrin repeat binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIF1AN itself. We selected most functions HIF1AN had, and list some proteins which have the same functions with HIF1AN. You can find most of the proteins on our site.

Function Related Protein
Notch bindingC8orf4;DNER;DLL1;NCOR2;SNW1;DLL4;NOTCH4;EGFL7;ADAM17
ankyrin repeat bindingSHANK1;HIF1AN;RELA
carboxylic acid bindingGOT1;PCK1;AKR1C21;GRHPR;AKR1C2;HMGCL;HIF1AN
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donorsTYW5;PHF8;KDM5B;JHDM1D;EGLN3;EGLN2;ALKBH8;ALKBH4;KDM5C
oxygen sensor activityHIF1AN;NOX4;EGLN2
peptidyl-asparagine 3-dioxygenase activity
peptidyl-histidine dioxygenase activity
protein bindingSSBP3;THEG;E2F3;NDE1;KRR1;EP300;CCDC24;BCL2A1A;ZNF26
protein homodimerization activityG6PDX;RELA;CECR1;PRKG2;RAG1;IZUMO3;GDF6;HAND1;TBX18
zinc ion bindingMTA1;RNF130;RNF166;KDM2AA;PAM;XIRP2;CXXC1B;LHX2A;ADH5

HIF1AN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIF1AN here. Most of them are supplied by our site. Hope this information will be useful for your research of HIF1AN.


Liu, Y; Zhang, LW; et al. DNA-PKcs Deficiency Inhibits Glioblastoma Cell-Derived Angiogenesis After Ionizing Radiation. JOURNAL OF CELLULAR PHYSIOLOGY 230:1094-1103(2015).
Shida, T; Nozawa, T; et al. Fluvastatin-induced reduction of oxidative stress ameliorates diabetic cardiomyopathy in association with improving coronary microvasculature. HEART AND VESSELS 29:532-541(2014).
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