ifnar2

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ifnar2

Official Full Name interferon (alpha and beta) receptor 2
Background This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1. IFNAR1 and IFNAR2 are coexpressed on nearly all cells and make up the heterodimeric receptor that binds a
Synonyms IFNAR2; interferon (alpha and beta) receptor 2; interferon alpha/beta receptor 2; IFN-R-2; interferon receptor 2c; IFN-alpha/beta receptor 2; type I interferon receptor 2; interferon-alpha/beta receptor 2; type I interferon alpha/beta receptor 2a; Ifnar-2
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cells
    • Mammalian Cell
    • NS0
    • Yeast
    • Tag :
    • Fc
    • Fc Chimera
    • GST
    • hIgG/His
    • His
    • T7
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFNAR2-003H Recombinant Human IFNAR2 Protein, hIgG/His-tagged Insect Cells hIgG/His
    Human IFNAR2-041H Recombinant Human IFNAR2 Protein, hIgG/His-tagged Insect cells hIgG/His
    Human IFNAR2-156HB Recombinant Human IFNAR2 protein, His-tagged, Biotinylated HEK293 His
    Mouse IFNAR2-2339M Recombinant Mouse IFNAR2 Protein (22-242 aa), His-tagged Yeast His
    Human IFNAR2-1152H Recombinant Human IFNAR2 protein, His & T7-tagged E.coli His/T7
    Human IFNAR2-14078H Recombinant Human IFNAR2, GST-tagged E.coli GST
    Human IFNAR2-156H Recombinant Human IFNAR2 protein, His-tagged HEK293 His
    Human IFNAR2-157H Recombinant Human IFNAR2 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human IFNAR2-214H Recombinant Human IFNAR2 Protein, Fc-tagged HEK293 Fc
    Human IFNAR2-2243HCL Recombinant Human IFNAR2 cell lysate Human Cell N/A
    Human IFNAR2-25H Recombinant Human IFNAR2, Fc Chimera HEK293 Fc
    Human IFNAR2-27987TH Recombinant Human IFNAR2, His-tagged His
    Human IFNAR2-3349H Recombinant Human IFNAR2, His tagged Human Cell His
    Human IFNAR2-6952H Recombinant Human Interferon(alpha, beta and omega) Receptor 2, Fc-tagged Human Cell Fc
    Mouse Ifnar2-683M Recombinant Mouse Ifnar2, Fc Chimera NS0 Fc Chimera
    Mouse IFNAR2-8038M Recombinant Mouse IFNAR2 Protein Mammalian Cell His
    Cynomolgus Monkey IFNAR2-1194C Recombinant Cynomolgus IFNAR2 Protein, His-tagged HEK293 His
    Chicken IFNAR2-6421C Recombinant Chicken IFNAR2 Mammalian Cell His

    ifnar2 involved in several pathways and played different roles in them. We selected most pathways ifnar2 participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ifnar2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IFNB1; RNF207B; Flt3l; CCL3L1; IFNAR2; CXCL12; IFNW1; GM1987; AMHR2; IL10RA
    PIK-Akt signaling pathway PIK3CB; IFNA17; Reln; TRP53; EPOR; PHLPP2; FGF1; CCND1; TP53; RELA
    Osteoclast differentiation NCF4; IFNAR1; NCF1; LILRA2; TAB2; LILRB1; SYK; NFKBIA; MAPK10; PPP3R1
    Toll-like receptor signaling pathway IFNA17; CD86; MAPK8B; CCL4; MAP2K2; TLR5B; TRAF6; TLR2-1; TLR9; TNF
    Jak-STAT signaling pathway IL11RA; HRAS; SOCS4; CNTF; CRFB2; AOX1; IL2RA; STAT3; STAT1B; CISH
    Natural killer cell mediated cytotoxicity IFNA13; IFNA2; PPP3CC; PIK3R5; ITGB2L; IFNA6; MAP2K2; MICB; LAT; PRF1
    Hepatitis C CLDN4; STAT3; PPP2R2C; CLDN7; EIF2AK4; IKBKG; IFNA7; OCLN; TP53; CLDN22
    Measles RAB9B; PIK3CA; TNFRSF10B; PIK3R3; CBLB; OAS3; EIF2AK2; RCHY1; PIK3CB; IL1B
    Influenza A OAS3; NUP98; IFNA7; IRF7; CCL5; IL33; OAS1A; MAP2K3; IL6; KPNA1
    Herpes simplex infection IFNGR1; MHC2DEB; Ifna11; IL15; IFNA13; TLR9; PPP1CC; CCL5; SRSF2B; IL12BA

    ifnar2 has several biochemical functions, for example, protein binding, protein kinase binding, type I interferon binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ifnar2 itself. We selected most functions ifnar2 had, and list some proteins which have the same functions with ifnar2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ODF2; HHIPL2; GPR37; TRIM2; TGFB2; KDM1A; BCAP31; Unc5b; L3MBTL3; SS18
    protein kinase binding DOK7; CASP9; CYLD; HSPB1; TRAP1; PRKACA; PAX6; Cd24a; RCC2; ELP2
    type I interferon binding IFNAR2
    type I interferon receptor activity IFNAR1; IFNAR2

    ifnar2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ifnar2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ifnar2.

    IRF9; JAK1; GNB2L1; CREBBP; STAT2; IFNA2

    Ovsyannikova, IG; Salk, HM; et al. Single-nucleotide polymorphism associations in common with immune responses to measles and rubella vaccines. IMMUNOGENETICS 66:663-669(2014).
    Kuruganti, S; Accavitti-Loper, MA; et al. Production and characterization of thirteen human type-I interferon-alpha Mark subtypes. PROTEIN EXPRESSION AND PURIFICATION 103:75-83(2014).

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