IFNAR2

  • Official Full Name

    interferon (alpha and beta) receptor 2

  • Overview

    This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1. IFNAR1 and IFNAR2 are coexpressed on nearly all cells and make up the heterodimeric receptor that binds a
  • Synonyms

    IFNAR2; interferon (alpha and beta) receptor 2; interferon alpha/beta receptor 2; IFN-R-2; interferon receptor 2c; IFN-alpha/beta receptor 2; type I interferon receptor 2; interferon-alpha/beta receptor 2; type I interferon alpha/beta receptor 2a; Ifnar-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Insect cells
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • C
  • Fc
  • hFc
  • His
  • Fc Chimera
  • GST
  • hIgG
  • His (Fc)
  • Avi
  • His|T7
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IFNAR2-6952H Active Recombinant Human Interferon(alpha, beta and omega) Receptor 2, Fc-tagged Human Cell Fc 458 amino acids
Human IFNAR2-25H Active Recombinant Human IFNAR2, Fc Chimera HEK293 Fc
Human IFNAR2-157H Active Recombinant Human IFNAR2 protein(Met1-Lys243), hFc-tagged HEK293 C-hFc Met1-Lys243
Human IFNAR2-214H Active Recombinant Human IFNAR2 protein, Fc-tagged HEK293 Fc Ile27-Lys243
Human IFNAR2-14078H Recombinant Human IFNAR2, GST-tagged E.coli GST 230-331a.a.
Human IFNAR2-27987TH Recombinant Human IFNAR2, His-tagged His
Human IFNAR2-3349H Recombinant Human IFNAR2 protein(Met1-Lys243), His-tagged HEK293 C-His Met1-Lys243
Human IFNAR2-156H Active Recombinant Human IFNAR2 protein, His-tagged HEK293 His Ile27-Lys243
Human IFNAR2-1152H Recombinant Human IFNAR2 protein, His & T7-tagged E.coli His/T7 Ile27~Lys243 (Accession # P48551)
Human IFNAR2-2243HCL Recombinant Human IFNAR2 cell lysate Human Cell N/A
Human IFNAR2-156HB Recombinant Human IFNAR2 protein, His-tagged, Biotinylated HEK293 His
Human IFNAR2-003H Recombinant Human IFNAR2 Protein, hIgG/His-tagged Insect Cells hIgG/His 27-243aa
Human IFNAR2-2568H Recombinant Human IFNAR2 Protein (Ile27-Lys243), C-Fc tagged Mammalian cells C-Fc Ile27-Lys243
Human IFNAR2-041H Recombinant Human IFNAR2 Protein, hIgG/His-tagged Insect cells hIgG/His
Human IFNAR2-296H Recombinant Human IFNAR2 Protein, Fc-tagged HEK293 Fc 515
Human IFNAR2-3073H Recombinant Human IFNAR2 protein, His-SUMO-tagged E.coli His-SUMO 27-243aa
Human IFNAR2-2569H Recombinant Human IFNAR2 Protein (Ile27-Lys243), C-His tagged Mammalian cells C-His Ile27-Lys243
Human IFNAR2-295H Recombinant Human IFNAR2 Protein, His-tagged HEK293 His 515
Human IFNAR2-2570H Recombinant Human IFNAR2 Protein (Ile27-Lys243), N-His tagged E.coli N-His Ile27-Lys243
Mouse Ifnar2-683M Active Recombinant Mouse Ifnar2, Fc Chimera Mammalian cells Fc Chimera
Mouse IFNAR2-8038M Recombinant Mouse IFNAR2 Protein Mammalian Cell His
Mouse Ifnar2-139M-B Recombinant Mouse Ifnar2 Protein Pre-coupled Magnetic Beads HEK293
Mouse IFNAR2-0238M Active Recombinant Mouse IFNAR2 protein, His-tagged HEK293 His Ser22-Ala242
Mouse Ifnar2-139M Recombinant Mouse Ifnar2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse IFNAR2-2339M Recombinant Mouse IFNAR2 Protein (22-242 aa), His-tagged Yeast His 22-242 aa
Rat IFNAR2-1303R Recombinant Rat IFNAR2 protein, His-tagged HEK293 His Phe 31 - Ala 244
Cynomolgus Monkey IFNAR2-1194C Recombinant Cynomolgus IFNAR2 Protein, His-tagged HEK293 His
Homo sapiens (Human) RFL23085HF Recombinant Full Length Human Interferon Alpha/Beta Receptor 2(Ifnar2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-515)
Chicken IFNAR2-6421C Recombinant Chicken IFNAR2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • IFNAR2 Related Signal Pathway

IFNAR2 involved in several pathways and played different roles in them. We selected most pathways IFNAR2 participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNAR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionCCR9A;PDGFAB;FLT3;TNFRSF14;MPL;IL10RB;ACKR3B;IL12A;IL19
PIK-Akt signaling pathwayGNB1;VEGFC;PIK3CB;PDGFB;FGFR1;THBS1;GSK3B;GNG3;TNC
Osteoclast differentiationIFNGR2;SIRP-BETA;PLCG2;NFKB1;IL1A;GAB2;MAPK9;LILRB3;CYLD
Toll-like receptor signaling pathwayCD14;IFNA10;IKBKE;IFNPHI1;IRAK4;MAPK12A;MAPK11;RELA;TAB2
Jak-STAT signaling pathwayRAF1A;IL2RA;LEP;AKT3A;CCND3;PIK3R1;IFNA5;IFNA8;SOCS1
Natural killer cell mediated cytotoxicityFCGR3A;IFNA13;VAV1;TNFRSF10D;KLRC1;FCGR3B;IFNA21;KIR3DL1;LCP2
Hepatitis CCLDN6;IFNA8;TLR3;CLDN23;AKT1;ARAF;PPP2R2A;CLDN20;IFNA5
MeaslesTBK1;IFNA4;IFNG;TLR2;STAT3;IL4;MSN;OAS1B;IFNA14
Influenza AFAS;NXF3;TMPRSS13;IFNB1;RELA;IFIH1;OAS3;HSPA1L;IFNA3
Herpes simplex infectionBLB2;CCL2;POLR2A;C3A.1;BF1;SRSF2;Ifna15;HLA-DQB1;CLOCKA

IFNAR2 has several biochemical functions, for example, protein binding, protein kinase binding, type I interferon binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNAR2 itself. We selected most functions IFNAR2 had, and list some proteins which have the same functions with IFNAR2. You can find most of the proteins on our site.

Function Related Protein
protein bindingNUS1;COMMD10;XRCC1;IK;UBB;GPX3;CDC26;HOMEZ;RAB8B
protein kinase bindingILK;RHEB;IKBKB;ITGB2;DLG1;EEF1A2;CAV2;FAM83B;PDGFRB
type I interferon binding
type I interferon receptor activityIFNAR1;IFNAR2

IFNAR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNAR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNAR2.

IRF9; JAK1; GNB2L1; CREBBP; STAT2; IFNA2

Gene Family

Cytokines

Research Area

Related articles

Ovsyannikova, IG; Salk, HM; et al. Single-nucleotide polymorphism associations in common with immune responses to measles and rubella vaccines. IMMUNOGENETICS 66:663-669(2014).
Kuruganti, S; Accavitti-Loper, MA; et al. Production and characterization of thirteen human type-I interferon-alpha Mark subtypes. PROTEIN EXPRESSION AND PURIFICATION 103:75-83(2014).
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