• Official Full Name

    interleukin 17B

  • Background

    The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.
  • Synonyms

    IL17B; interleukin 17B; interleukin-17B; IL 17B; IL 20; MGC138900; MGC138901; neuronal interleukin 17 related factor; NIRF; ZCYTO7; interleukin 20; interleukin-20; cytokine Zcyto7; interleukin-17 beta; cytokine-like protein ZCYTO7; neuronal interleukin-17;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • Fc
    • Avi
    • His
    • His (Fc)
    • His(C
    • ter)
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL17B-166H Recombinant Human Interleukin 17B E.coli N/A
    Human IL17B-29741TH Recombinant Human IL17B protein E.coli N/A
    Human IL17B-5244HCL Recombinant Human IL17B 293 Cell Lysate HEK293 N/A
    Human IL17B-317H Active Recombinant Human interleukin 17B, HIgG1 Fc-tagged CHO Fc
    Human IL17B-150H Recombinant Active Human IL17B Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human IL17B-562H Recombinant Human interleukin 17B, His-tagged E.coli His
    Human IL17B-316H Active Recombinant Human interleukin 17B, HIgG1 Fc-tagged, mutant CHO Fc
    Human IL17B-136H Recombinant Human IL17B protein, His-tagged Insect Cell His
    Human IL17B-1869H Recombinant Human IL17B protein, Fc-tagged HEK293 Fc
    Human IL17B-942H Recombinant Human IL17B Protein, His-tagged E.coli His
    Human IL17B-315H Active Recombinant Human interleukin 17B, MIgG2a Fc-tagged CHO Fc
    Human IL17B-0191H Recombinant Human IL17B protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi
    Human IL17B-439H Recombinant Human IL17B Protein, Fc-tagged Insect Cell Fc
    Mouse IL17B-4495M Recombinant Mouse IL17B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Il17b-289M Recombinant Mouse Interleukin 17B, His-tagged Insect Cell His
    Mouse Il17b-01M Active Recombinant Mouse Il17b Protein, His-Tagged E.coli His
    Mouse IL17B-4495M-B Recombinant Mouse IL17B Protein Pre-coupled Magnetic Beads HEK293
    Mouse Il17b-513M Recombinant Mouse Il17b, Fc-tagged Insect Cell Fc
    Mouse IL17B-8121M Recombinant Mouse IL17B Protein Mammalian Cell His
    Mouse Il17b-440M Recombinant Mouse Il17b protein, Fc-tagged Insect Cell Fc
    Rat Il17b-1821R Recombinant Rat Il17b protein, His-tagged E.coli His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL17B Related Gene Family
    • IL17B Related Research Area

    IL17B involved in several pathways and played different roles in them. We selected most pathways IL17B participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionCXCL12;PRL2;BMP7A;IL22RA1;TNFRSF9A;CXCR7;TNFRSF1B;CXCL3;Ccl21c

    IL17B has several biochemical functions, for example, cytokine activity, cytokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17B itself. We selected most functions IL17B had, and list some proteins which have the same functions with IL17B. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activityLIF;BMP6;GDF10B;NDP;TGFB2;GDF15;CCL38.1;Ccl12;IL36RN
    cytokine receptor bindingIL17A/F2;IL15;IL17A/F3;IFNA5;MIF;IFNPHI1;IFNA3;IL17C;IL17A/F1

    IL17B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17B here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17B.


    • Q&As
    • Reviews

    Q&As (10)

    Ask a question
    What strategies are employed to investigate the cross-talk between IL17B and other cytokines in inflammatory responses? 09/01/2022

    Co-culture experiments and signaling pathway analysis reveal IL17B's interaction with other cytokines.

    How does IL17B's structure affect its receptor binding affinity, and what experimental techniques reveal this? 07/16/2022

    Techniques like surface plasmon resonance elucidate IL17B's binding to its receptor.

    How is the impact of IL17B on cancer progression studied using in vivo models? 05/01/2022

    In vivo models combine IL17B overexpression or neutralization with tumor models to study its role.

    What experimental designs are used to understand the role of IL17B in tissue-specific inflammation in human samples? 08/16/2021

    Human tissue samples are analyzed using immunohistochemistry and cytokine profiling to understand IL17B's effects.

    Can you elaborate on the techniques used to determine IL17B's role in modulating immune cell behavior? 12/16/2020

    Flow cytometry and functional assays explore how IL17B affects immune cell activation and cytokine production.

    What are the approaches to analyzing IL17B's involvement in neuroinflammation and central nervous system disorders? 07/05/2019

    Research uses animal models and biomarker analysis to study IL17B in neuroinflammatory diseases.

    Can you explain the use of genetic knockout or knockdown techniques to validate IL17B's functional effects? 05/24/2019

    Genetic techniques like CRISPR/Cas9 knockout or siRNA knockdown validate IL17B's functional impact.

    Could you detail the experimental protocols to assess the effect of IL17B on endothelial barrier function? 07/06/2018

    Transwell assays and impedance-based methods evaluate IL17B's impact on endothelial barrier integrity.

    How do researchers identify the downstream signaling pathways activated by IL17B and its receptor? 11/01/2017

    Western blotting and phosphorylation assays uncover IL17B's downstream signaling pathways.

    What experimental methods differentiate IL17B from other IL17 family members during gene expression analysis? 04/12/2017

    Gene expression analysis involves qPCR or RNA sequencing to distinguish IL17B expression patterns.

    Customer Reviews (3)

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      Suitable for signaling studies. -


        High solubility -


          Potent in B-cell assays. -

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