IL17RD

  • Official Full Name

    IL17RD interleukin 17 receptor D

  • Overview

    Fibroblast growth factors (FGFs; see MIM 603726) are secreted proteins involved in cellular proliferation, migration, differentiation, and survival. FGF activity is negatively regulated by members of the sprouty family (e.g., SPRY1, MIM 602465). The SEF protein is a modulator of FGF signaling.
  • Synonyms

    IL17RD; interleukin 17 receptor D; interleukin-17 receptor D; FLJ35755; IL 17RD; IL17RLM; SEF; hSef; IL17Rhom; sef homolog; IL-17 receptor D; interleukin-17 receptor-like protein; IL-17RD; MGC133309; DKFZp434N1928;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • Fc
  • Flag
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL17RD-404H Active Recombinant Human IL17RD, His-tagged Mammalian cells His
Human IL17RD-724HFL Active Recombinant Full Length Human IL17RD Protein, C-Flag-tagged Mammalian cells Flag
Human IL17RD-766H Recombinant Human IL17RD protein(Met1-Arg299), His-tagged HEK293 C-His Met1-Arg299
Human IL17RD-7983H Recombinant Human IL17RD protein, His-tagged E.coli His Thr157~Arg299 (Accession # Q8NFM7)
Human IL17RD-2919HCL Recombinant Human IL17RD cell lysate Human Cell N/A
Human IL17RD-3145H-B Recombinant Human IL17RD Protein Pre-coupled Magnetic Beads HEK293
Human IL17RD-4842H Recombinant Human IL17RD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL17RD-3145H Recombinant Human IL17RD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Il17rd-814M Active Recombinant Mouse Il17rd Protein, His-tagged Mammalian cells His Gly28-Arg299
Mouse Il17rd-5650M Recombinant Mouse Interleukin 17 receptor D, His-tagged Mammalian cells His
Mouse Il17rd-7984M Recombinant Mouse Il17rd protein, His-tagged E.coli His Pro356-Val603 (Accession # Q8JZL1)
Mouse IL17RD-8128M Recombinant Mouse IL17RD Protein Mammalian Cell His
Mouse Il17rd-4498M-B Recombinant Mouse Il17rd Protein Pre-coupled Magnetic Beads HEK293
Mouse Il17rd-3502M Recombinant Mouse Il17rd Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Il17rd-4498M Recombinant Mouse Il17rd Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Il17rd-7985R Recombinant Rat Il17rd protein, His & T7-tagged E.coli His/T7 Pro356~Glu605 (Accession # D3ZGQ0)
Canine IL17RD-174C Recombinant Canine IL17RD, His-tagged Human Cell His Ala27-Arg299
Canine IL17RD-1054C Recombinant Canine IL17RD Protein, Fc-tagged HEK293 Fc
Canine IL17RD-001CCL Recombinant Canine IL17RD cell lysate Human Cell N/A
Zebrafish IL17RD-9467Z Recombinant Zebrafish IL17RD Mammalian Cell His
Chicken IL17RD-6084C Recombinant Chicken IL17RD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IL17RD involved in several pathways and played different roles in them. We selected most pathways IL17RD participated on our site, such as ARMS-mediated activation, Axon guidance, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ARMS-mediated activationFRS2A;PAQR3A;PEA15A;RASGEF1A;SPTBN2;SPTBN1;DUSP2;SPNA2;SPRED1
Axon guidanceEPHA4;SEMA4C;ARPC5;NRP2;COL9A1A;ROCK2;RND1;DUSP9;EPHA8
Cytokine Signaling in Immune systemIRF2;PEBP1;EIF4E;PTPRA;FRS2;DUSP1;TRIM68;PELI1;MX2
DAP12 interactionsNEFLB;FGF8B;FGF18B;AGO2;GRAP2B;DUSP2;SIRPB1;AHCYL1;SPRED2
DAP12 signalingNRG4;PEBP1;PAQR3B;SPRED1;SPRED3;DUSP6;DUSP10;DAB2IPB;PTPRA
Developmental BiologyMARK3;SDCBP;SCN2A;LGI3;PEBP1;MYOD1;MED6;EFNB1;MEF2AA
Downstream signal transductionFGF8B;TRAT1;FGF10B;AGO1;FGFR1B;THEM4;CNKSR1;DUSP9;FGF18B
Downstream signaling of activated FGFR1PEA15;CNKSR1;SPNA1;PAQR3B;WDR83;PHB;SPTB;PAQR3A;RASGRP4

IL17RD has several biochemical functions, for example, interleukin-17 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RD itself. We selected most functions IL17RD had, and list some proteins which have the same functions with IL17RD. You can find most of the proteins on our site.

Function Related Protein
interleukin-17 receptor activityIL17RC;IL17RD;IL17RA;IL17RB;IL17RE

IL17RD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RD here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RD.

Gene Family

IL

Research Area

Related articles

Ota, M; Yanagisawa, M; et al. A significant induction of neutrophilic chemoattractants but not RANKL in synoviocytes stimulated with interleukin 17. JOURNAL OF BONE AND MINERAL METABOLISM 33:40-47(2015).
Amaral, LM; Kiprono, L; et al. Progesterone supplementation attenuates hypertension and the autoantibody to the angiotensin II type I receptor in response to elevated interleukin-6 during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 211:-(2014).
  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
12/22/2020

    Potent in anti-inflammatory assays.

    04/25/2019

      High bioactivity.

      04/13/2019

        Good for receptor studies.

        Q&As (10)

        Ask a question
        What experimental strategies are employed to understand the expression patterns and regulation of IL17RD across different tissues and cell types? 07/29/2021

        RT-qPCR, single-cell RNA sequencing, and immunohistochemistry reveal IL17RD expression patterns and regulatory mechanisms.

        What experimental methods are used to investigate the involvement of IL17RD in the crosstalk between different immune signaling pathways? 10/30/2020

        Co-stimulation assays, pathway-specific inhibitors, and gene expression profiling elucidate IL17RD's cross-pathway interactions.

        What methodologies are employed to assess the impact of IL17RD on immune cell differentiation, activation, and cytokine production? 07/23/2020

        Flow cytometry, functional assays, and gene expression analysis investigate IL17RD's impact on immune cell functions.

        Could you explain how genetic manipulation, such as knockout or knockdown, of IL17RD in animal models helps decipher its physiological functions? 11/24/2019

        Knockout mice, CRISPR-based models, and tissue-specific ablation provide insights into IL17RD's functions in vivo.

        How are molecular and structural biology approaches utilized to uncover the binding partners or ligands that interact with IL17RD? 10/28/2019

        Yeast two-hybrid screens, co-crystallization, and surface plasmon resonance uncover IL17RD's interacting partners or ligands.

        How do researchers study the potential therapeutic applications of targeting IL17RD in immune-related disorders? 08/06/2019

        Preclinical studies, therapeutic antibodies, and disease models assess IL17RD as a potential target for immune-related conditions.

        How are insights from experimental studies on IL17RD translated into clinical research to evaluate its relevance in human diseases? 01/22/2019

        Clinical trials, biomarker validation, and patient stratification evaluate IL17RD's clinical relevance and potential therapies.

        How do researchers experimentally distinguish IL17RD's specific contributions within the broader IL17 receptor family? 10/16/2018

        Functional assays, co-immunoprecipitation, and knockout models distinguish IL17RD's specific roles within the IL17 receptor family.

        What cellular and functional assays are used to elucidate the downstream signaling events triggered by IL17RD activation and their implications for immune responses? 01/04/2018

        Reporter gene assays, phosphoprotein analysis, and cytokine profiling unveil IL17RD-mediated signaling cascades and immune outcomes.

        Can you elaborate on the techniques used to investigate IL17RD's potential role as a co-receptor or modulator of IL17 signaling pathways? 08/14/2017

        Biophysical analyses, mutation studies, and chimeric receptor assays explore IL17RD's role in modulating IL17 signaling.

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