IL17RD

  • Official Full Name

    IL17RD interleukin 17 receptor D

  • Background

    Fibroblast growth factors (FGFs; see MIM 603726) are secreted proteins involved in cellular proliferation, migration, differentiation, and survival. FGF activity is negatively regulated by members of the sprouty family (e.g., SPRY1, MIM 602465). The SEF protein is a modulator of FGF signaling.
  • Synonyms

    IL17RD; interleukin 17 receptor D; interleukin-17 receptor D; FLJ35755; IL 17RD; IL17RLM; SEF; hSef; IL17Rhom; sef homolog; IL-17 receptor D; interleukin-17 receptor-like protein; IL-17RD; MGC133309; DKFZp434N1928;
    • Type:
    • Cell & Tissue Lysates
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Canine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Mammalian cells
    • Tag :
    • Fc
    • His
    • His (Fc)
    • Avi
    • His|T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Canine IL17RD-001CCL Recombinant Canine IL17RD cell lysate Human Cell N/A
    Canine IL17RD-1054C Recombinant Canine IL17RD Protein, Fc-tagged HEK293 Fc
    Canine IL17RD-174C Recombinant Canine IL17RD, His-tagged Human Cell His
    Chicken IL17RD-6084C Recombinant Chicken IL17RD Mammalian Cell His
    Human IL17RD-7983H Recombinant Human IL17RD protein, His-tagged E.coli His
    Human IL17RD-766H Recombinant Human IL17RD, His tagged Human Cell His
    Human IL17RD-3145H-B Recombinant Human IL17RD Protein Pre-coupled Magnetic Beads HEK293
    Human IL17RD-2919HCL Recombinant Human IL17RD cell lysate Human Cell N/A
    Human IL17RD-404H Active Recombinant Human IL17RD, His-tagged Mammalian cells His
    Human IL17RD-4842H Recombinant Human IL17RD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IL17RD-3145H Recombinant Human IL17RD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Il17rd-7984M Recombinant Mouse Il17rd protein, His-tagged E.coli His
    Mouse Il17rd-5650M Recombinant Mouse Interleukin 17 receptor D, His-tagged Mammalian cells His
    Mouse Il17rd-814M Active Recombinant Mouse Il17rd Protein, His-tagged Mammalian cells His
    Mouse Il17rd-4498M-B Recombinant Mouse Il17rd Protein Pre-coupled Magnetic Beads HEK293
    Mouse IL17RD-8128M Recombinant Mouse IL17RD Protein Mammalian Cell His
    Mouse Il17rd-4498M Recombinant Mouse Il17rd Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Il17rd-3502M Recombinant Mouse Il17rd Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat Il17rd-7985R Recombinant Rat Il17rd protein, His & T7-tagged E.coli His/T7
    Zebrafish IL17RD-9467Z Recombinant Zebrafish IL17RD Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL17RD Related Articles
    • IL17RD Related Gene Family
    • IL17RD Related Research Area

    IL17RD involved in several pathways and played different roles in them. We selected most pathways IL17RD participated on our site, such as ARMS-mediated activation, Axon guidance, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ARMS-mediated activationHBEGF;DUSP2;PSMD5;CRK;PSME3;IL17RD;PEBP1;WDR83;DUSP6
    Axon guidancePAK3;MAPK3;KLB;ABL1;DUSP6;ITGB1;SPNA1;SCN9A;SLIT1
    Cytokine Signaling in Immune systemDUSP4;PELI2;OSTN;IRF4;NUP35;GBP1;TRIM6;CISH;IFIT8
    DAP12 interactionsKBTBD7;DUSP9;FGF8B;NEFLB;DUSP5;CSF2RB;KLB;PEA15;NRG4
    DAP12 signalingGRAP2A;AGO2;HBEGF;FRS2A;FGF20A;DUSP6;FRS2;DUSP2;SPNA1
    Developmental BiologyMYL12A;JAK3;LGI1;COL4A5;SPTA1;PSPN;ARPC2;SPRED1;ACVR1C
    Downstream signal transductionPEA15;RASGEF1A;CNKSR1;FGF8B;PEBP1;DAB2IPB;AGO3;DUSP2;CRKL
    Downstream signaling of activated FGFR1CNKSR1;SPRED1;DAB2IPB;PEA15A;RASGRP4;PHB;PTPRA;IL17RD;SPNA1

    IL17RD has several biochemical functions, for example, interleukin-17 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RD itself. We selected most functions IL17RD had, and list some proteins which have the same functions with IL17RD. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-17 receptor activityIL17RD;IL17RB;IL17RC;IL17RE;IL17RA

    IL17RD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RD here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RD.

    Ota, M; Yanagisawa, M; et al. A significant induction of neutrophilic chemoattractants but not RANKL in synoviocytes stimulated with interleukin 17. JOURNAL OF BONE AND MINERAL METABOLISM 33:40-47(2015).
    Amaral, LM; Kiprono, L; et al. Progesterone supplementation attenuates hypertension and the autoantibody to the angiotensin II type I receptor in response to elevated interleukin-6 during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 211:-(2014).
    IL
    • Q&As
    • Reviews

    Q&As (10)

    Ask a question
    What experimental strategies are employed to understand the expression patterns and regulation of IL17RD across different tissues and cell types? 07/29/2021

    RT-qPCR, single-cell RNA sequencing, and immunohistochemistry reveal IL17RD expression patterns and regulatory mechanisms.

    What experimental methods are used to investigate the involvement of IL17RD in the crosstalk between different immune signaling pathways? 10/30/2020

    Co-stimulation assays, pathway-specific inhibitors, and gene expression profiling elucidate IL17RD's cross-pathway interactions.

    What methodologies are employed to assess the impact of IL17RD on immune cell differentiation, activation, and cytokine production? 07/23/2020

    Flow cytometry, functional assays, and gene expression analysis investigate IL17RD's impact on immune cell functions.

    Could you explain how genetic manipulation, such as knockout or knockdown, of IL17RD in animal models helps decipher its physiological functions? 11/24/2019

    Knockout mice, CRISPR-based models, and tissue-specific ablation provide insights into IL17RD's functions in vivo.

    How are molecular and structural biology approaches utilized to uncover the binding partners or ligands that interact with IL17RD? 10/28/2019

    Yeast two-hybrid screens, co-crystallization, and surface plasmon resonance uncover IL17RD's interacting partners or ligands.

    How do researchers study the potential therapeutic applications of targeting IL17RD in immune-related disorders? 08/06/2019

    Preclinical studies, therapeutic antibodies, and disease models assess IL17RD as a potential target for immune-related conditions.

    How are insights from experimental studies on IL17RD translated into clinical research to evaluate its relevance in human diseases? 01/22/2019

    Clinical trials, biomarker validation, and patient stratification evaluate IL17RD's clinical relevance and potential therapies.

    How do researchers experimentally distinguish IL17RD's specific contributions within the broader IL17 receptor family? 10/16/2018

    Functional assays, co-immunoprecipitation, and knockout models distinguish IL17RD's specific roles within the IL17 receptor family.

    What cellular and functional assays are used to elucidate the downstream signaling events triggered by IL17RD activation and their implications for immune responses? 01/04/2018

    Reporter gene assays, phosphoprotein analysis, and cytokine profiling unveil IL17RD-mediated signaling cascades and immune outcomes.

    Can you elaborate on the techniques used to investigate IL17RD's potential role as a co-receptor or modulator of IL17 signaling pathways? 08/14/2017

    Biophysical analyses, mutation studies, and chimeric receptor assays explore IL17RD's role in modulating IL17 signaling.

    Customer Reviews (3)

    Write a review
    Reviews
    12/22/2020

      Potent in anti-inflammatory assays. -

      04/25/2019

        High bioactivity. -

        04/13/2019

          Good for receptor studies. -

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