IL17RD
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Official Full Name
IL17RD interleukin 17 receptor D
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Overview
Fibroblast growth factors (FGFs; see MIM 603726) are secreted proteins involved in cellular proliferation, migration, differentiation, and survival. FGF activity is negatively regulated by members of the sprouty family (e.g., SPRY1, MIM 602465). The SEF protein is a modulator of FGF signaling. -
Synonyms
IL17RD; interleukin 17 receptor D; interleukin-17 receptor D; FLJ35755; IL 17RD; IL17RLM; SEF; hSef; IL17Rhom; sef homolog; IL-17 receptor D; interleukin-17 receptor-like protein; IL-17RD; MGC133309; DKFZp434N1928;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Canine
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human Cell
- Mammalian Cell
- Mammalian cells
- Fc
- Flag
- His
- Avi
- T7
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
IL17RD involved in several pathways and played different roles in them. We selected most pathways IL17RD participated on our site, such as ARMS-mediated activation, Axon guidance, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17RD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ARMS-mediated activation | SPRED2;PEBP1;CSK;JAK1;FRS3;CSF2;DUSP1;FRS2A;WDR83 |
| Axon guidance | PAK4;ROBO1;SPTBN2;CREB1B;SRGAP3;PEA15;FRS2B;MARK3;SEMA6A |
| Cytokine Signaling in Immune system | IRF2;HLA-DQB2;IFITM2;FCGR1B;CISH;EIF4E3;TRIM22;IFIT10;TRIM45 |
| DAP12 interactions | DUSP9;CNKSR1;FRS2B;LAMTOR2;PEA15A;SPNA2;PAQR3A;JAK3;CSF2RB |
| DAP12 signaling | FGF8B;GRAP2A;LCP2A;WDR83;JAK3;DUSP10;NRG3;PEA15A;PHB |
| Developmental Biology | PLXND1;POU5F3;LGI1B;MED26;AP2S1;ARPC1B;EPHA2A;DUSP7;PAQR3A |
| Downstream signal transduction | FGF18B;DUSP9;AGO3;JAK1;FGFR1B;FRS2A;SPRED3;DUSP10;SPRED2 |
| Downstream signaling of activated FGFR1 | SPTA1;SPTB;IL17RD;PTPRA;PHB;PAQR3B;PAQR3A;RASGRP4;WDR83 |
IL17RD has several biochemical functions, for example, interleukin-17 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17RD itself. We selected most functions IL17RD had, and list some proteins which have the same functions with IL17RD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| interleukin-17 receptor activity | IL17RD;IL17RC;IL17RA;IL17RE;IL17RB |
IL17RD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17RD here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17RD.
Gene Family
Research Area
Related articles
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Customer Reviews (3)
Write a reviewPotent in anti-inflammatory assays.
High bioactivity.
Good for receptor studies.
Q&As (10)
Ask a questionRT-qPCR, single-cell RNA sequencing, and immunohistochemistry reveal IL17RD expression patterns and regulatory mechanisms.
Co-stimulation assays, pathway-specific inhibitors, and gene expression profiling elucidate IL17RD's cross-pathway interactions.
Flow cytometry, functional assays, and gene expression analysis investigate IL17RD's impact on immune cell functions.
Knockout mice, CRISPR-based models, and tissue-specific ablation provide insights into IL17RD's functions in vivo.
Yeast two-hybrid screens, co-crystallization, and surface plasmon resonance uncover IL17RD's interacting partners or ligands.
Preclinical studies, therapeutic antibodies, and disease models assess IL17RD as a potential target for immune-related conditions.
Clinical trials, biomarker validation, and patient stratification evaluate IL17RD's clinical relevance and potential therapies.
Functional assays, co-immunoprecipitation, and knockout models distinguish IL17RD's specific roles within the IL17 receptor family.
Reporter gene assays, phosphoprotein analysis, and cytokine profiling unveil IL17RD-mediated signaling cascades and immune outcomes.
Biophysical analyses, mutation studies, and chimeric receptor assays explore IL17RD's role in modulating IL17 signaling.
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