Active Recombinant Full Length Human IL17RD Protein, C-Flag-tagged

• Cat.No.: IL17RD-724HFL
• Product Overview: Recombinant Full Length Human IL17RD Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Co-immunoprecipitation
• Molecular Mass: 82.2 kDa
• AA Sequence: MAPWLQLCSVFFTVNACLNGSQLAV AAGGSGRARGADTCGWRGVGPASRN SGLYNITFKYDNCTTYLNPV GKHVIADAQNITISQYACHDQVAVT ILWSPGALGIEFLKGFRVILEELKS EGRQCQQLILKDPKQLNSSF KRTGMESQPFLNMKFETDYFVKVVP FPSIKNESNYHPFFFRTRACDLLLQ PDNLACKPFWKPRNLNISQH GSDMQVSFDHAPHNFGFRFFYLHYK LKHEGPFKRKTCKQEQTTETTSCLL QNVSPGDYIIELVDDTNTTR KVMHYALKPVHSPWAGPIRAVAITV PLVVISAFATLFTVMCRKKQQENIY SHLDEESSESSTYTAALPRE RLRPRPKVFLCYSSKDGQNHMNVVQ CFAYFLQDFCGCEVALDLWEDFSLC REGQREWVIQKIHESQFIIV VCSKGMKYFVDKKNYKHKGGGRGSG KGELFLVAVSAIAEKLRQAKQSSSA ALSKFIAVYFDYSCEGDVPG ILDLSTKYRLMDNLPQLCSHLHSRD HGLQEPGQHTRQGSRRNYFRSKSGR SLYVAICNMHQFIDEEPDWF EKQFVPFHPPPLRYREPVLEKFDSG LVLNDVMCKPGPESDFCLKVEAAVL GATGPADSQHESQHGGLDQD GEARPALDGSAALQPLLHTVKAGSP SDMPRDSGIYDSSVPSSELSLPLME GLSTDQTETSSLTESVSSSS
  GLGEEEPPALPSKLLSSGSCKADLG CRSYTDELHAVAPLTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: IL17RD interleukin 17 receptor D [ Homo sapiens (human) ]
• Official Symbol: IL17RD
• Synonyms: SEF; HH18; IL-17RD; IL17RLM
• Gene ID: 54756
• mRNA Refseq: NM_017563.5
• Protein Refseq: NP_060033.3
• MIM: 606807
• UniProt ID: Q8NFM7