Recombinant Mouse Interleukin 17 receptor D, His-tagged

Cat.No. : Il17rd-5650M
Product Overview : RecombinantMouse Il17rd protein was expressed in Murine myeloma cellline. Gly28-Arg299,with a C-terminal 6-His tag.
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Cat. No. : Il17rd-5650M
Description : Il17rd isa type I transmembrane protein that is found in both the cytoplasm and plasmamembrane. The gene for this protein belongs to a synexpression group originallyidentified in zebrafish and SEF is expressed along with FGF-3, -8, sprouty-2(SPRY2) and SPRY4. Due to the presence of an alternate start site, there isone transcript that potentially gives rise to two isoforms. The first is a full-lengthlong form and the second an N-terminally truncated form.
Source : Mammalian cells
Form : Lyophilized from a0.2 um filtered solution in PBS with BSA as a carrier protein.
N-terminalSequence : Gly28
MolecularWeight : 31.6 kDa
Activity : Bioassaydata are not available.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 54-60kDa, reducing conditions.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 100 μg/mLin sterile PBS containing at least 0.1% human or bovine serum albumin
Storage : Use a manual defrost freezer and avoid repeated freeze-thawcycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
Gene Name : Il17rd interleukin 17 receptorD [ Mus musculus ]
Official Symbol : Il17rd
Synonyms : Il17rd; interleukin17 receptor D; Sef; Sef-S; AI428510; 2810004A10Rik; interleukin-17receptor D; mSef; IL-17RD; sef homolog; IL-17 receptor D; interleukin-17receptor-like protein
Gene ID : 171463
mRNA Refseq : NM_134437
Protein Refseq : NP_602319
UniProt ID : Q3KQI3
Chromosome Location : 14
Function : receptor activity;zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What experimental strategies are employed to understand the expression patterns and regulation of IL17RD across different tissues and cell types? 07/29/2021

RT-qPCR, single-cell RNA sequencing, and immunohistochemistry reveal IL17RD expression patterns and regulatory mechanisms.

What experimental methods are used to investigate the involvement of IL17RD in the crosstalk between different immune signaling pathways? 10/30/2020

Co-stimulation assays, pathway-specific inhibitors, and gene expression profiling elucidate IL17RD's cross-pathway interactions.

What methodologies are employed to assess the impact of IL17RD on immune cell differentiation, activation, and cytokine production? 07/23/2020

Flow cytometry, functional assays, and gene expression analysis investigate IL17RD's impact on immune cell functions.

Could you explain how genetic manipulation, such as knockout or knockdown, of IL17RD in animal models helps decipher its physiological functions? 11/24/2019

Knockout mice, CRISPR-based models, and tissue-specific ablation provide insights into IL17RD's functions in vivo.

How are molecular and structural biology approaches utilized to uncover the binding partners or ligands that interact with IL17RD? 10/28/2019

Yeast two-hybrid screens, co-crystallization, and surface plasmon resonance uncover IL17RD's interacting partners or ligands.

How do researchers study the potential therapeutic applications of targeting IL17RD in immune-related disorders? 08/06/2019

Preclinical studies, therapeutic antibodies, and disease models assess IL17RD as a potential target for immune-related conditions.

How are insights from experimental studies on IL17RD translated into clinical research to evaluate its relevance in human diseases? 01/22/2019

Clinical trials, biomarker validation, and patient stratification evaluate IL17RD's clinical relevance and potential therapies.

How do researchers experimentally distinguish IL17RD's specific contributions within the broader IL17 receptor family? 10/16/2018

Functional assays, co-immunoprecipitation, and knockout models distinguish IL17RD's specific roles within the IL17 receptor family.

What cellular and functional assays are used to elucidate the downstream signaling events triggered by IL17RD activation and their implications for immune responses? 01/04/2018

Reporter gene assays, phosphoprotein analysis, and cytokine profiling unveil IL17RD-mediated signaling cascades and immune outcomes.

Can you elaborate on the techniques used to investigate IL17RD's potential role as a co-receptor or modulator of IL17 signaling pathways? 08/14/2017

Biophysical analyses, mutation studies, and chimeric receptor assays explore IL17RD's role in modulating IL17 signaling.

Customer Reviews (3)

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Reviews
12/22/2020

    Potent in anti-inflammatory assays.

    04/25/2019

      High bioactivity.

      04/13/2019

        Good for receptor studies.

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