Active Recombinant Human IL17RD, His-tagged

Cat.No. : IL17RD-404H
Product Overview : Recombinant Human IL17RD (Accession # AAM77571) Ala27-Arg299, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.
  • Specification
  • Gene Information
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Source : Mammalian cells
Species : Human
Tag : His
Predicted N Terminal : Ala27
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Bioassay data are not available.Immobilized recombinant human IL-36 beta at 1 µg/mL (100 µL/well) can bind recombinant human IL-1 Rrp2 Fc Chimera with a linear range of 0.15 - 5 µg/mL.
Molecular Mass : Recombinant Human IL17RD, His-tagged has a calculated MW of 32 kDa. In SDS-PAGE migrates as 55-63 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 50 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : IL17RD interleukin 17 receptor D [ Homo sapiens ]
Official Symbol : IL17RD
Synonyms : IL17RD; interleukin 17 receptor D; interleukin-17 receptor D; FLJ35755; IL 17RD; IL17RLM; SEF; hSef; IL17Rhom; sef homolog; IL-17 receptor D; interleukin-17 receptor-like protein; IL-17RD; MGC133309; DKFZp434N1928;
Gene ID : 54756
mRNA Refseq : NM_017563
Protein Refseq : NP_060033
MIM : 606807
UniProt ID : Q8NFM7
Chromosome Location : 3p21.1

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◆ Lysates
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Related Gene

IL10 IL10RA IL10RB IL11 IL11RA Il11ra1 IL12 IL12A IL12B IL12RB1 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL16 IL17A IL17B Il17c IL17D Il17f IL17RA IL17RD IL18 IL18BP IL18R1 IL18RAP Il19 Il1a IL1B IL1F10 IL1R1 Il1r2 IL1RAP IL1RAPL1 IL1RAPL2 IL1RL1 IL1RL2 Il1rn IL2 Il20 IL20RA IL21 IL21R IL22 IL22RA1 IL22RA2 IL23A IL24 Il25 IL27 IL27RA IL28A Il28b IL29 IL2RA IL2RB Il2rg IL3 IL31 IL32 Il33 Il34 IL3RA IL4 IL4R Il4ra Il5 IL5RA Il6 IL6R Il6ra IL6ST Il7 IL7R IL8 IL9 IL36A Il12rb2 IL17RB IL23R IL26 IL31RA IL36B IL36G IL36RN IL37 IL9R IL17RC IL17RE IL28RA IL4I1 IL20RB Il11ra2 IL7RA Il23a&Il12b

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What experimental strategies are employed to understand the expression patterns and regulation of IL17RD across different tissues and cell types? 07/29/2021

RT-qPCR, single-cell RNA sequencing, and immunohistochemistry reveal IL17RD expression patterns and regulatory mechanisms.

What experimental methods are used to investigate the involvement of IL17RD in the crosstalk between different immune signaling pathways? 10/30/2020

Co-stimulation assays, pathway-specific inhibitors, and gene expression profiling elucidate IL17RD's cross-pathway interactions.

What methodologies are employed to assess the impact of IL17RD on immune cell differentiation, activation, and cytokine production? 07/23/2020

Flow cytometry, functional assays, and gene expression analysis investigate IL17RD's impact on immune cell functions.

Could you explain how genetic manipulation, such as knockout or knockdown, of IL17RD in animal models helps decipher its physiological functions? 11/24/2019

Knockout mice, CRISPR-based models, and tissue-specific ablation provide insights into IL17RD's functions in vivo.

How are molecular and structural biology approaches utilized to uncover the binding partners or ligands that interact with IL17RD? 10/28/2019

Yeast two-hybrid screens, co-crystallization, and surface plasmon resonance uncover IL17RD's interacting partners or ligands.

How do researchers study the potential therapeutic applications of targeting IL17RD in immune-related disorders? 08/06/2019

Preclinical studies, therapeutic antibodies, and disease models assess IL17RD as a potential target for immune-related conditions.

How are insights from experimental studies on IL17RD translated into clinical research to evaluate its relevance in human diseases? 01/22/2019

Clinical trials, biomarker validation, and patient stratification evaluate IL17RD's clinical relevance and potential therapies.

How do researchers experimentally distinguish IL17RD's specific contributions within the broader IL17 receptor family? 10/16/2018

Functional assays, co-immunoprecipitation, and knockout models distinguish IL17RD's specific roles within the IL17 receptor family.

What cellular and functional assays are used to elucidate the downstream signaling events triggered by IL17RD activation and their implications for immune responses? 01/04/2018

Reporter gene assays, phosphoprotein analysis, and cytokine profiling unveil IL17RD-mediated signaling cascades and immune outcomes.

Can you elaborate on the techniques used to investigate IL17RD's potential role as a co-receptor or modulator of IL17 signaling pathways? 08/14/2017

Biophysical analyses, mutation studies, and chimeric receptor assays explore IL17RD's role in modulating IL17 signaling.

Customer Reviews (3)

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Reviews
12/22/2020

    Potent in anti-inflammatory assays. -

    04/25/2019

      High bioactivity. -

      04/13/2019

        Good for receptor studies. -

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