IL17RE

Therapeutic antibody development, in vivo efficacy studies, and disease models explore IL17RE as a potential target for immune-related therapies.

Clinical studies, biomarker validation, and patient stratification efforts connect IL17RE's experimental findings to its clinical implications.

X-ray crystallography, cryo-electron microscopy, and molecular modeling provide insights into IL17RE's ligand recognition and conformational changes.

Transcriptomics, immunohistochemistry, and in vitro culture systems explore IL17RE's expression patterns and responses to diverse stimuli.

Comparative functional assays, co-stimulation studies, and knockout models help discern IL17RE's distinct contributions and receptor interactions.

Flow cytometry, cytokine assays, and immune cell co-culture models assess IL17RE's impact on immune cell functions and cytokine production.

Ligand-receptor interaction assays, proteomic analyses, and mutational studies identify IL17RE's binding partners and downstream effectors.

Knockout mice, CRISPR-mediated gene editing, and adoptive transfer experiments unravel IL17RE's roles in vivo and its contributions to diseases.

Phosphorylation assays, luciferase reporter systems, and cytokine profiling dissect IL17RE-mediated signaling cascades and immune outcomes.

Patient samples, disease models, and in vitro inflammation models probe IL17RE's involvement in autoimmune and inflammatory pathogenesis.