Recombinant Human IL17RE, GST-tagged

Cat.No. : IL17RE-14161H
Product Overview : Recombinant Human IL17RE protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Availability July 19, 2024
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Description : This gene encodes a protein that shares limited similarity with the interleukin-17 receptor. The function of the encoded protein has not yet been determined. Alternatively spliced transcript variants have been described.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-271a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : IL17RE interleukin 17 receptor E [ Homo sapiens ]
Official Symbol : IL17RE
Synonyms : IL17RE; interleukin 17 receptor E; interleukin-17 receptor E; FLJ23658; IL-17 receptor E; MGC71884;
Gene ID : 132014
mRNA Refseq : NM_001193380
Protein Refseq : NP_001180309
UniProt ID : Q8NFR9
Chromosome Location : 3p25.3
Function : receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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02/20/2022

    Effective in T-cell activation.

    03/18/2021

      High specificity.

      08/11/2018

        Suitable for ELISA.

        Q&As (10)

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        How do researchers study the potential therapeutic applications of targeting IL17RE in the context of immune-related conditions? 06/28/2022

        Therapeutic antibody development, in vivo efficacy studies, and disease models explore IL17RE as a potential target for immune-related therapies.

        How are insights gained from experimental studies on IL17RE integrated into translational research to advance our understanding of its clinical relevance? 05/24/2022

        Clinical studies, biomarker validation, and patient stratification efforts connect IL17RE's experimental findings to its clinical implications.

        How are molecular and structural biology approaches utilized to understand the binding interfaces and conformational changes of IL17RE in complex with its ligands? 05/20/2022

        X-ray crystallography, cryo-electron microscopy, and molecular modeling provide insights into IL17RE's ligand recognition and conformational changes.

        Can you elaborate on the techniques used to investigate IL17RE's tissue-specific expression patterns and its regulation under various physiological conditions? 11/24/2021

        Transcriptomics, immunohistochemistry, and in vitro culture systems explore IL17RE's expression patterns and responses to diverse stimuli.

        How do researchers experimentally differentiate IL17RE's roles within the IL17 receptor family and its potential crosstalk with other family members? 07/12/2021

        Comparative functional assays, co-stimulation studies, and knockout models help discern IL17RE's distinct contributions and receptor interactions.

        Could you explain the methodologies researchers use to assess the impact of IL17RE on immune cell differentiation, cytokine production, and immune responses? 12/28/2020

        Flow cytometry, cytokine assays, and immune cell co-culture models assess IL17RE's impact on immune cell functions and cytokine production.

        What experimental strategies are employed to identify the ligands or signaling molecules that interact with IL17RE and contribute to downstream signaling? 10/06/2019

        Ligand-receptor interaction assays, proteomic analyses, and mutational studies identify IL17RE's binding partners and downstream effectors.

        What animal models, genetic manipulation techniques, and in vivo assays are used to elucidate IL17RE's physiological functions and its involvement in diseases? 08/26/2019

        Knockout mice, CRISPR-mediated gene editing, and adoptive transfer experiments unravel IL17RE's roles in vivo and its contributions to diseases.

        What cellular assays and functional readouts are used to dissect the intracellular signaling pathways triggered by IL17RE activation and their implications? 08/19/2018

        Phosphorylation assays, luciferase reporter systems, and cytokine profiling dissect IL17RE-mediated signaling cascades and immune outcomes.

        What experimental methods are employed to investigate the potential role of IL17RE in the pathogenesis of autoimmune diseases or inflammatory disorders? 04/14/2018

        Patient samples, disease models, and in vitro inflammation models probe IL17RE's involvement in autoimmune and inflammatory pathogenesis.

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