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Official Full Name interleukin 18 receptor 1
Background The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to
Synonyms IL18R1; interleukin 18 receptor 1; interleukin-18 receptor 1; CD218 antigen-like family member A; CD218a; CDw218a; CDw218a antigen; IL 1Rrp; IL-18R-1; IL-18R1; IL-1Rrp; IL1 receptor related protein; IL1 receptor-related protein; IL18R_HUMAN; IL18RA; Il18ralpha; IL1R-rp; IL1RRP; Interleukin 18 receptor, alpha chain; interleukin 1 receptor related protein
    • Species :
    • Canine
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NSO
    • Rabbit
    • Tag :
    • Fc
    • His
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL18R1-14163H Recombinant Human IL18R1, His-tagged E.coli His
    Human IL18R1-1657H Recombinant Human Interleukin 18 Receptor 1 NSO N/A
    Human IL18R1-165H Recombinant Human IL18R1 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human IL18R1-1749H Recombinant Human IL18R1 protein, His-tagged E.coli His
    Human IL18R1-191H Recombinant Human IL18R1, His-tagged HEK293 His
    Human IL18R1-2035H Recombinant Human IL18R1 Protein, Fc/His-tagged HEK293 Fc/His
    Human Il18r1-2207M Recombinant Mouse Interleukin 18 Receptor 1, His-tagged Human Cell His
    Human IL18R1-2253H Recombinant Human IL18R1, His tagged Human Cell His
    Human IL18R1-2254H Recombinant Human IL18R1, Fc-His tagged Human Cell Fc/His
    Human IL18R1-2587HCL Recombinant Human IL18R1 cell lysate Human Cell N/A
    Mouse CAB11563RM Rabbit Anti-Mouse Interleukin-18 Receptor 1 Monoclonal Antibody Rabbit N/A
    Mouse Il18r1-1750M Recombinant Mouse Il18r1 protein, His-tagged E.coli His
    Mouse Il18r1-1751M Recombinant Mouse Il18r1 protein, His-tagged E.coli His
    Mouse IL18R1-2785MCL Recombinant Mouse IL18R1 cell lysate Human Cell N/A
    Mouse Il18r1-3319M Recombinant Mouse Il18r1, Fc-His tagged Human Cell Fc/His
    Mouse Il18r1-839M Recombinant Mouse Il18r1 Protein, His-tagged HEK293 His
    Rat IL18R1-163R Recombinant Rat Il18r1, His tagged Human Cell His
    Rat Il18r1-7454R Recombinant Rat Il18r1, Fc tagged Human Cell Fc
    Rat IL18R1-829RCL Recombinant Rat IL18R1 cell lysate Human Cell N/A
    Cynomolgus Monkey IL18R1-001CCL Recombinant Cynomolgus IL18R1 cell lysate Human Cell N/A
    Cynomolgus Monkey IL18R1-207C Recombinant Cynomolgus IL18R1, His-tagged Human Cell His
    Cynomolgus Monkey IL18R1-81C Recombinant Cynomolgus IL18R1, Fc tagged Human Cell Fc
    Canine IL18R1-1048C Recombinant Canine IL18R1 Protein, His-tagged HEK293 His
    Canine IL18R1-173C Recombinant Canine IL18R1, Fc tagged Human Cell His
    Canine IL18R1-837CCL Recombinant Canine IL18R1 cell lysate Human Cell N/A
    Chicken IL18R1-3911C Recombinant Chicken IL18R1 Mammalian Cell His

    il18r1 involved in several pathways and played different roles in them. We selected most pathways il18r1 participated on our site, such as Cytokine-cytokine receptor interaction, TNF signaling pathway, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with il18r1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IFNE; TNFSF8; ACVR1; VEGFAA; OSM; NGFRB; BMPR1BB; IFNB1; INHBB; CXCL16
    TNF signaling pathway IL6; MAP3K7; PIK3R1; NFKB1; MAP3K14; Ccl12; CASP7; RELA; MAP2K1; PIK3R2
    Inflammatory bowel disease (IBD) IL4; TGFB1; HLA-DPB1; Il23a; Il12b; Il23a; HLA-DQA2; IFNG; IL18; RELA; HLA-DMA

    il18r1 has several biochemical functions, for example, interleukin-1 receptor activity, interleukin-18 receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by il18r1 itself. We selected most functions il18r1 had, and list some proteins which have the same functions with il18r1. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-1 receptor activity IL1RL2; IL1R2; IL1RAP; IL1RL1; IL1RAPL2; IL1R1; IL18R1; IL1RAPL1A
    interleukin-18 receptor activity IL18R1
    protein binding THRB; FAS; ETV4; HDAC7; ZFYVE9; AP1S2; ATF1; OSBPL6; ROCK1; ATP1A2
    receptor activity PLXNA1; CD160; PVRL3; VMN1R47; LILRA2; GABRA5; TNFRSF13B; NLGN1; DERL1; GRIN1B

    il18r1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with il18r1 here. Most of them are supplied by our site. Hope this information will be useful for your research of il18r1.


    Ovsyannikova, IG; Haralambieva, IH; et al. Genetic Variation in IL18R1 and IL18 Genes and Inteferon gamma ELISPOT Response to Smallpox Vaccination: An Unexpected Relationship. JOURNAL OF INFECTIOUS DISEASES 208:1422-1430(2013).
    Haralambieva, IH; Ovsyannikova, IG; et al. Common SNPs/Haplotypes in IL18R1 and IL18 Genes Are Associated With Variations in Humoral Immunity to Smallpox Vaccination in Caucasians and African Americans. JOURNAL OF INFECTIOUS DISEASES 204:433-441(2011).


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