Active Recombinant Human IL18R1 protein, Fc-His-tagged

• Cat.No.: IL18R1-2254H
• Product Overview: Active Recombinant Human IL18R1 protein(NP_003846.1) (Met 1-Arg 329) was expressed in HEK293, fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc&His
• Protein Length: 1-329 aa
• Form: Lyophilized from sterile PBS, pH 7.4.
• Bio-activity: Measured by its ability to bind cynomolgus IL-18 in a functional ELISA.
• Molecular Mass: The recombinant human IL18R1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 559 amino acids and has a predicted molecular mass of 64 kDa. As a result of glycosylation, the apparent molecular mass of rh IL18R1/Fc monomer is approximately 95-110 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 70 % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• protein Refseq-Weblink: http://www.ncbi.nlm.nih.gov/protein/NP_003846.1
• Unit ID: Q13478
• Unit ID-Weblink: https://www.uniprot.org/uniprotkb/Q13478

Gene Information

• Gene Name: IL18R1 interleukin 18 receptor 1 [ Homo sapiens ]
• Official Symbol: IL18R1
• Synonyms: IL18R1; interleukin 18 receptor 1; interleukin-18 receptor 1; CD218a; IL 1Rrp; IL1RRP; IL-18R1; IL1R-rp; IL-18R-1; cytokine receptor; IL1 receptor-related protein; CD218 antigen-like family member A; IL18RA; CDw218a; IL-1Rrp
• Gene ID: 8809
• mRNA Refseq: NM_003855
• protein Refseq: NP_003846
• MIM: 604494