Recombinant Human Interleukin 18 Receptor 1 IL18R1-1657H

Recombinant Human Interleukin 18 Receptor 1


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Cat.No. : IL18R1-1657H Optional Service: Optional requirements on this protein
Description : The interleukin-18 receptor 1 (IL-18R1) is a cytokine receptor of the immunoglobulin superfamily. IL18R1 is also known as IL-18Rα, CDw218a (cluster of differentiation w218a), IL-1Rrp, and IL-1R family member. IL-18R1 specifically binds to interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IL-18Rα is expressed on Th1 cells, NK cell subset, neutrophils and IL-12-stimulated tonsillar B cells. By itself, IL-18Rα binds IL-18 with low affinity and when complexed with IL-18Rβ chain binds IL-18 with high affinity. The proinflammatory cytokine IL-18 and its receptor complex play an important role in the innate and autoimmune responses.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-18 Rα is Mr 63 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 95-105 kDa.
Source : Mammalian cells
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : IL18R1 interleukin 18 receptor 1 [ Homo sapiens ]
Synonyms : IL18R1; interleukin 18 receptor 1; CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp; cytokine receptor; OTTHUMP00000161340; OTTHUMP00000203113; IL1 receptor-related protein; CD218 antigen-like family member A; CD218a antigen; cytokine receptor; Interleukin-18 receptor 1
Gene ID : 8809
mRNA Refseq : NM_003855
Protein Refseq : NP_003846
MIM : 604494
UniProt ID : Q13478
Chromosome Location : 2q12
Pathway : Cytokine-cytokine receptor interaction
Function : interleukin-1 receptor activity; transmembrane receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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