itgb3bp

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itgb3bp

Official Full Name integrin beta 3 binding protein (beta3-endonexin)
Background This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Synonyms ITGB3BP; integrin beta 3 binding protein (beta3-endonexin); centromere protein R; CENPR; HSU37139; NRIF3; TAP20; Beta3 endonexin; CENP R; Integrin beta 3 binding protein; NRIF 3; Nuclear receptor interacting factor 3; TAP 20; beta 3 endonexin; beta-3-endonexin; OTTHUMP00000015392; OTTHUMP00000015409; OTTHUMP00000015410; integrin beta-3-binding protein; nuclear receptor-interacting factor 3; CENP-R
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ITGB3BP-180H Recombinant Human ITGB3BP, GST-tagged E.coli GST
    Human ITGB3BP-4975H Recombinant Human ITGB3BP Protein, GST-tagged Wheat Germ GST
    Human ITGB3BP-5123HCL Recombinant Human ITGB3BP 293 Cell Lysate HEK293 N/A
    Human ITGB3BP-543H Recombinant Human integrin beta 3 binding protein (beta3-endonexin), His-tagged E.coli His
    Rat ITGB3BP-3115R Recombinant Rat ITGB3BP Protein Mammalian Cell His
    Chicken ITGB3BP-3450C Recombinant Chicken ITGB3BP Mammalian Cell His

    itgb3bp involved in several pathways and played different roles in them. We selected most pathways itgb3bp participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Cell death signalling via NRAGE, NRIF and NADE, which may be useful for your reference. Also, other proteins which involved in the same pathway with itgb3bp were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle LIN37; CTDNEP1; CTDNEP1B; RAD9A; USO1; SMC3; CENPA; TOP2A; KIF20A; VRK2
    Cell Cycle, Mitotic DYRK1A; TMPO; VRK1; CENPN; CENPE; TMEM188; KIF2C; NIPBL; CEP76; KIF20A
    Cell death signalling via NRAGE, NRIF and NADE ARHGEF1A; ITSN1; KALRNB; ARHGEF9; ITGB3BP; ARHGEF16; KALRN; FGD2; TRIO; ECT2
    Chromosome Maintenance CENPN; POT1; RBBP4; DKC1; CENPO; POT1A; DNA2; RUVBL2; CENPP; TERF1
    Deposition of new CENPA-containing nucleosomes at the centromere CENPQ; APITD1; OIP5; CENPH; RBBP7; NPM1; CENPK; CENPO; PANE1; CENPA
    M Phase STAG1; CTDNEP1; DSN1; ENSA; ARPP19; CENPN; CENPI; CLIP1; SKA2; MAU2
    Mitotic Anaphase CDCA8; INCENP; KNTC1; SKA1; CENPK; AHCTF1; CENPO; SPDL1; ZWILCH; CENPH
    Mitotic Metaphase and Anaphase SGOL1; CENPL; ZWINT; CDCA8; RANGAP1B; TMPO; CENPN; PMF1; AHCTF1; CENPC1

    itgb3bp has several biochemical functions, for example, protein C-terminus binding, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by itgb3bp itself. We selected most functions itgb3bp had, and list some proteins which have the same functions with itgb3bp. You can find most of the proteins on our site.

    Function Related Protein
    protein C-terminus binding XRCC4; BLOC1S2A; SDC1; CDC20; PPP2CB; YWHAQ; VPS4A; BCL10; NEFL; CTBP1
    protein binding PPP2R2C; C1S; ELOVL6; TIMP2; HSPA1B; CAMLG; ERLEC1; MOAP1; CYTH2; AKAP5
    signal transducer activity MAS1; TAAR15; PROKR1A; OR103-4; GPR139; OLFR5; GPR30; RGS9B; RERG; MTNR1AA

    itgb3bp has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with itgb3bp here. Most of them are supplied by our site. Hope this information will be useful for your research of itgb3bp.

    ARFIP2; COL4A3BP; KIFC3; HIP1; SVIL; KDM1A; OFD1; WFS1; RECQL5; ALDH2; PDHA1; ACTG1

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