Recombinant Full Length Human ITGB3BP Protein, C-Flag-tagged
Cat.No. : | ITGB3BP-1967HFL |
Product Overview : | Recombinant Full Length Human ITGB3BP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 20 kDa |
AA Sequence : | MPVKRSLKLDGLLEENSFDPSKITR KKSVITYSPTTGTCQMSLFASPTSS EEQKHRNGLSNEKRKKLNHP SLTESKESTTKDNDEFMMLLSKVEK LSEEIMEIMQNLSSIQALEGSRELE NLIGISCASHFLKREMQKTK ELMTKVNKQKLFEKSTGLPHKASRH LDSYEFLKAILN TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Gene Name : | ITGB3BP integrin subunit beta 3 binding protein [ Homo sapiens (human) ] |
Official Symbol : | ITGB3BP |
Synonyms : | CENPR; NRIF3; TAP20; CENP-R; HSU37139 |
Gene ID : | 23421 |
mRNA Refseq : | NM_014288.5 |
Protein Refseq : | NP_055103.3 |
MIM : | 605494 |
UniProt ID : | Q13352 |
Products Types
◆ Recombinant Protein | ||
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ITGB3BP-2771R | Recombinant Rat ITGB3BP Protein, His (Fc)-Avi-tagged | +Inquiry |
ITGB3BP-1217H | Recombinant Human ITGB3BP Protein, His (Fc)-Avi-tagged | +Inquiry |
Itgb3bp-3607M | Recombinant Mouse Itgb3bp Protein, Myc/DDK-tagged | +Inquiry |
ITGB3BP-180H | Recombinant Human ITGB3BP, GST-tagged | +Inquiry |
◆ Lysates | ||
ITGB3BP-5123HCL | Recombinant Human ITGB3BP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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