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Official Full Name Integrin, Beta 6
Background Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene.
Synonyms ITGB6; integrin, beta 6; OTTHUMP000001628962; OTTHUMP00000205127; OTTHUMP00000205128; OTTHUMP000002073332
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ITGAV & ITGB6-760H Recombinant Human ITGAV & ITGB6 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Mouse Itgb6-460M Recombinant Mouse ITGB6 Protein HEK293 N/A
    Human ITGA5&ITGB6-854HCL Recombinant Human ITGA5&ITGB6 cell lysate Human Cell N/A
    Human ITGA5-164H Recombinant Human ITGA5 & ITGB6, Flag & His tagged Human Cell His
    Human ITGAV&ITGB6-741H Recombinant Human ITGAV&ITGB6 CHO N/A
    Human ITGB6-253H Recombinant Human ITGB6 Protein, His-tagged E.coli His
    Human ITGB6-29868TH Recombinant Human ITGB6 Wheat Germ N/A
    Human ITGB6-4968H Recombinant Human ITGB6 Protein, GST-tagged Wheat Germ GST
    Human ITGB6-5122HCL Recombinant Human ITGB6 293 Cell Lysate HEK293 N/A
    Mouse Itgb6-254M Recombinant Mouse Itgb6 Protein, His-tagged E.coli His
    Rat ITGB6-3117R Recombinant Rat ITGB6 Protein Mammalian Cell His

    itgb6 involved in several pathways and played different roles in them. We selected most pathways itgb6 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with itgb6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway Itga10&Itgb1; FGF2; RXRA; FGF14; ITGA2B; PPP2R5A; IL3; GNG10; TNC; FGF22
    Focal adhesion PIK3R5; VEGFAA; VEGFA; Reln; SEPP1; PRKCBB; ITGB8; RHOAB; SHC2; ARHGAP35
    ECM-receptor interaction TNXB; ITGA6; SPP1; COL11A1A; FN1; ITGB5; COL2A1B; COL4A5; COL3A1; SV2A
    Regulation of actin cytoskeleton FGF1A; ITGB3B; Itga10&Itgb1; GIT1; MSNB; FGFR1A; VCLA; RHOAB; PTK2; PIP5K1AB
    Hypertrophic cardiomyopathy (HCM) CACNA2D3; CACNB4; ITGA2; ITGA10; CACNG7; ITGA6; ACTC1; PRKAG3; PRKAB2; DMD
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) RYR2; ITGA8; SGCB; CACNA2D2; ACTB; CTNNA3; ITGB8; CACNG4; ITGB1; SGCA
    Dilated cardiomyopathy MYBPC3; ITGA4; CACNB1; ACTB; ITGB6; DMD; ITGB8; IGF1; CACNB4; CACNG7

    itgb6 has several biochemical functions, for example, integrin binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by itgb6 itself. We selected most functions itgb6 had, and list some proteins which have the same functions with itgb6. You can find most of the proteins on our site.

    Function Related Protein
    integrin binding THY1; WISP1; ITGA3; FBLN1; ACTN1; ADAMTS8; FCER2; L1CAM; LAMB2; ADAM23
    virus receptor activity SLC52A2; LAMP1; PVRL4; CR1; CD46; CR2; NCAM1; IDE; ICAM1; SCARB2

    itgb6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with itgb6 here. Most of them are supplied by our site. Hope this information will be useful for your research of itgb6.

    Tiezzi, F; Parker-Gaddis, KL; et al. A Genome-Wide Association Study for Clinical Mastitis in First Parity US Holstein Cows Using Single-Step Approach and Genomic Matrix Re-Weighting Procedure. PLOS ONE 10:-(2015).
    Moore, KM; Thomas, GJ; et al. Therapeutic Targeting of Integrin alpha v beta 6 in Breast Cancer. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 106:-(2014).

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