Recombinant Human ITGB6 Protein, GST-tagged

• Cat.No.: ITGB6-4968H
• Product Overview: Human ITGB6 full-length ORF ( NP_000879.2, 1 a.a. - 788 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 112.3 kDa
• AA Sequence: MGIELLCLFFLFLGRNDHVQGGCAL GGAETCEDCLLIGPQCAWCAQENFT HPSGVGERCDTPANLLAKGCQLNFI ENPVSQVEILKNKPLSVGRQKNSSD IVQIAPQSLILKLRPGGAQTLQVHV RQTEDYPVDLYYLMDLSASMDDDLN TIKELGSRLSKEMSKLTSNFRLGFG SFVEKPVSPFVKTTPEEIANPCSSI PYFCLPTFGFKHILPLTNDAERFNE IVKNQKISANIDTPEGGFDAIMQAA VCKEKIGWRNDSLHLLVFVSDADSH FGMDSKLAGIVIPNDGLCHLDSKNE YSMSTVLEYPTIGQLIDKLVQNNVL LIFAVTQEQVHLYENYAKLIPGATV GLLQKDSGNILQLIISAYEELRSEV ELEVLGDTEGLNLSFTAICNNGTLF QHQKKCSHMKVGDTASFSVTVNIPH CERRSRHIIIKPVGLGDALELLVSP ECNCDCQKEVEVNSSKCHHGNGSFQ CGVCACHPGHMGPRCECGEDMLSTD SCKEAPDHPSCSGRGDCYCGQCICH LSPYGNIYGPYCQCDNFSCVRHKGL LCGGNGDCDCGECVCRSGWTGEYCN CTTSTDSCVSEDGVLCSGRGDCVCG KCVCTNPGASGPTCERCPTCGDPCN SKRSCIECHLSAAGQAREECVDKCK LAGATISEEEDFSKDGSVSCSLQGE NECLITFLITTDNEGKTIIHSINEK DCPKPPNIPMIMLGVSLAILLIGVV LLCIWKLLVSFHDRKEVAKFEAERS KAKWQTGTNPLYRGSTSTFKNVTYK HREKQKVDLSTDC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ITGB6 integrin, beta 6 [ Homo sapiens ]
• Official Symbol: ITGB6
• Synonyms: ITGB6; integrin, beta 6; integrin beta-6
• Gene ID: 3694
• mRNA Refseq: NM_000888
• Protein Refseq: NP_000879
• MIM: 147558
• UniProt ID: P18564