ITGB7
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Official Full Name
integrin, beta 7 -
Overview
Integrin beta-7 is a protein that in humans is encoded by the ITGB7 gene. -
Synonyms
ITGB7;integrin, beta 7;integrin beta-7;Gut homing receptor beta subunit;Integrin beta 7 subunit;Integrin beta-P;ITB7;ITB7_HUMAN;Ly69;M290 IEL antigen;OTTHUMP00000242064;OTTHUMP00000242065;OTTHUMP00000242066
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Mammalian Cells
- HEK293
- E.coli
- In Vitro Cell Free System
- Non
- His
- Avi
- Fc
- Flag
- DDK
- Myc
- GST
Involved Pathway
ITGB7 involved in several pathways and played different roles in them. We selected most pathways ITGB7 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGB7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hypertrophic cardiomyopathy (HCM) | PRKAG3,LAMA2,TNNI3,PRKAB2,MYL3,ITGA2B,ITGB3,ITGA7,DAG1,ITGB1 |
| Cell adhesion molecules (CAMs) | CLDN15LA,CLDN11A,OCLNB,MPZL1,HLA-DQA1,H2-AB1,ITGA8,LRRC4B,F11R.1,H2-AA |
| Transcriptional misregulation in cancer | HMGA2,TGFBR2,GZMB,Aff1,TLX1,IL3,NCOR1,RARA,TLX3,ATM |
| Dilated cardiomyopathy | TPM4,SGCB,TGFB1,ACTC1,CACNG6,CACNG7,ITGA7,PLN,ITGA5,Itga10&Itgb1 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | CACNB1,CACNA2D1,ACTB,SGCA,CACNB2,DAG1,CTNNA1,LMNA,ITGB4,ITGA2 |
| ne network for IgA production | TNFRSF17,TNFSF13,CXCR4B,MHC2DCB,PIGR,HLA-DRA,HLA-DOB,HLA-DPA1,HLA-DMA,CCR9A |
| PIK-Akt signaling pathway | CCND2,IL3,KLK1B4,FGF9,GNG7,Ifna15,PHLPP2,SOS1,FGF3,GNG12 |
| Intestinal i | TGFB1,MAP3K14,HLA-DOB,HLA-DRA,H2-AA,MHC2DEB,HLA-DRB4,CXCL12,CD28,IL5 |
| ECM-receptor interaction | VTNB,VTNA,COL4A2,COL5A2A,THBS1,DAG1,ITGA8,LAMB1,COL4A4,FN1 |
Protein Function
ITGB7 has several biochemical functions, for example, cell adhesion molecule binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGB7 itself. We selected most functions ITGB7 had, and list some proteins which have the same functions with ITGB7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | GRIN2A,MOXD1L,APTX,KLF15,HBAE3,ZNF559,CECR1A,MEP1A.1,GNAT1,TDRD1 |
| cell adhesion molecule binding | PVRL4,CADM4,ADAM8,JUP,NRXN3,PVR,CADM2A,NRXN1,TENM2,AMICA1 |
| virus receptor activity | TFRC,ACE2,LDLR,CLDN1,PVRL4,NCAM1,AXL,SIVA1,CR1,GPR172B |
| protein binding | THRB,CALR,TRIM39,DCTN5,GORASP2,EPS15,IL36RN,ATP6V0A4,FFAR2,CLPB |
Interacting Protein
ITGB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGB7.
FLNA;Dok1;Apba1;Apba2;Tln1;Dab1;Dab2;Shc1;TNS2;ANKS1B;Numb;GULP1;RABGAP1
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