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Official Full Name integrin, beta 7
Background Integrin beta-7 is a protein that in humans is encoded by the ITGB7 gene.
Synonyms ITGB7; integrin, beta 7; integrin beta-7; Gut homing receptor beta subunit; Integrin beta 7 subunit; Integrin beta-P; ITB7; ITB7_HUMAN; Ly69; M290 IEL antigen; OTTHUMP00000242064; OTTHUMP00000242065; OTTHUMP00000242066
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ITGA4 & ITGB7-163H Recombinant Human ITGA4 & ITGB7 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Human ITGB7-26863TH Recombinant Human ITGB7 Wheat Germ N/A
    Human ITGB7-28499TH Recombinant Human ITGB7 Wheat Germ N/A
    Human ITGB7-4966H Recombinant Human ITGB7 Protein, GST-tagged Wheat Germ GST
    Human ITGB7-5121HCL Recombinant Human ITGB7 293 Cell Lysate HEK293 N/A
    Mouse ITGB7-8371M Recombinant Mouse ITGB7 Protein Mammalian Cell His

    itgb7 involved in several pathways and played different roles in them. We selected most pathways itgb7 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with itgb7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway RPS6KB1; MAP2K2; SGK3; FGF2; PDGFB; KITLG; NRAS; PCK1; INSR; IFNA12
    Focal adhesion VAV1; TNXB; THBS1; GRB2A; ITGA3B; ITGB8; VEGFB; PAK3; COL11A2; VCLA
    ECM-receptor interaction THBS4A; TNR; COL2A1B; THBS3A; LAMB3; Reln; COL1A2; COL6A4; ITGA3B; COL5A1
    Cell adhesion molecules (CAMs) CLDNJ; CD22; F11R; JAM2A; NADL1.2; H2-Q10; NLGN3; NRXN1; CD8B; CLDND
    Intestinal i CD40LG; HLA-DOB; HLA-DRB4; BMA2; CXCL12B; HLA-DQA2; TNFRSF13B; IL4; IL-15RA; HLA-DRA
    ne network for IgA production CD40; CD86; HLA-DOB; CXCR4B; HLA-DPA1; ITGA4; CXCL12B; MHC2DCB; IL15; BLB2
    Regulation of actin cytoskeleton ITGAE; RAF1; ITGA2; RASSF7; RHOAD; GIT1; GSN; PTK2AB; ITGA4; DIAPH1
    Transcriptional misregulation in cancer MLLT3; WT1; CD86; FLI1; ETV4; H3F3C; CEBPE; FCGR1A; MYCN; MLLT1
    Hypertrophic cardiomyopathy (HCM) ITGA10; TGFB3; TGFB2; CACNG6; Itga10&Itgb1; MYH7; SGCB; LMNA; CACNB4; PRKAB1
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) CACNG1; Itga10&Itgb1; SGCD; SGCA; ITGB3; CACNG6; ITGB4; TCF7; ITGA6; DSP
    Dilated cardiomyopathy CACNG1; ITGA3; PLN; ITGA1; CACNB4; TGFB1; CACNG2; PRKACA; MYH7; DES

    itgb7 has several biochemical functions, for example, cell adhesion molecule binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by itgb7 itself. We selected most functions itgb7 had, and list some proteins which have the same functions with itgb7. You can find most of the proteins on our site.

    Function Related Protein
    cell adhesion molecule binding JUP; TIGIT; NPTN; PTBP3; SELL; PVRL1; PKP3; PVRL1A; SMAGP; NRXN1
    metal ion binding NEK11; ZNF133; CYB561; OVOL1; MAP2K2; ZFP36L1; A3GALT2; SIRT7; PRKCQ; ZFP750
    protein binding TRIM63; SULT1E1; CHD8; NDUFA4; ZFHX3; KLF11; ZCCHC13; SYT6; PYCARD; INO80E
    virus receptor activity ITGA5; CLEC4M; CLEC5A; MRC1; ITGAV; CD4; IDE; ITGB5; SLC20A2; CR2

    itgb7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with itgb7 here. Most of them are supplied by our site. Hope this information will be useful for your research of itgb7.

    FLNA; Dok1; Apba1; Apba2; Tln1; Dab1; Dab2; Shc1; TNS2; ANKS1B; Numb; GULP1; RABGAP1

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